Frequency of Anemia in Patients with Heart Failure Admitted to Cardiology Unit of Tertiary Care Hospital
DOI:
https://doi.org/10.70749/ijbr.v3i6.1695Keywords:
Anemia, Heart Failure, NYHA Class, Hemoglobin, Prevalence, CardiologyAbstract
Background: Anemia is a common but often underdiagnosed comorbidity in patients with heart failure (HF), contributing to increased morbidity, hospitalizations, and reduced quality of life. Objective: This study aimed to determine the frequency of anemia among HF patients admitted to a tertiary care cardiology unit and explore associated clinical factors. Methods: This cross-sectional study was conducted at the Department of Cardiology, NICVD, Karachi, from February to May 2024. A total of 191 patients aged 40–80 years with a confirmed diagnosis of HF were enrolled using non-probability consecutive sampling. Patients with chronic kidney disease, blood dyscrasias, recent transfusions, malignancy, or iron supplementation were excluded. Hemoglobin levels were assessed to determine anemia status. Results: Among 191 patients, 89 (46.6%) were found to have anemia. Anemia was significantly more common in patients aged ≥60 years (p = 0.01), with longer disease duration (p = 0.02), BMI <25 kg/m² (p = 0.03), and NYHA class III–IV (p < 0.001). Although female patients had a higher prevalence of anemia, the association was not statistically significant (p = 0.08). Conclusion: Anemia is highly prevalent among heart failure patients, particularly in those who are elderly, underweight, or have advanced functional class or chronic disease. Routine screening and timely management of anemia should be integrated into heart failure care protocols to improve patient outcomes.
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Benjamin, E. J., Muntner, P., Alonso, A., Bittencourt, M. S., Callaway, C. W., Carson, A. P., ... & American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. (2019). Heart disease and stroke statistics—2019 update: a report from the American Heart Association. Circulation, 139(10), e56-e528.
https://doi.org/10.1161/CIR.0000000000000659
Pereira, C. A., Roscani, M. G., Zanati, S. G., & Matsubara, B. B. (2013). Anemia, heart failure and clinical management. Arquivos Brasileiros de Cardiologia, 101(1), 87-92.
https://doi.org/10.5935/abc.20130126
Sirbu, O. (2018). Anemia in heart failure - from guidelines to controversies and challenges. The Anatolian Journal of Cardiology.
https://doi.org/10.14744/anatoljcardiol.2018.08634
Anand, I. S., & Gupta, P. (2018). Anemia and iron deficiency in heart failure. Circulation, 138(1), 80-98.
https://doi.org/10.1161/circulationaha.118.030099
Ikama, M., Nsitou, B., Kocko, I., Mongo, N., Kimbally-Kaky, G., & Nkoua, J. (2015). Prevalence of anaemia among patients with heart failure at the Brazzaville University hospital: Cardiovascular topic. Cardiovascular Journal Of Africa, 26(3), 140-142.
https://doi.org/10.5830/cvja-2015-021
Natella, P., Le Corvoisier, P., Paillaud, E., Renaud, B., Mahé, I., Bergmann, J., Perchet, H., Mottier, D., Montagne, O., & Bastuji-Garin, S. (2017). Long-term mortality in older patients discharged after acute decompensated heart failure: A prospective cohort study. BMC Geriatrics, 17(1).
https://doi.org/10.1186/s12877-017-0419-2
Przybylowski, P., Wasilewski, G., Golabek, K., Bachorzewska-Gajewska, H., Dobrzycki, S., Koc-Zorawska, E., & Malyszko, J. (2016). Absolute and functional iron deficiency is a common finding in patients with heart failure and after heart transplantation. Transplantation Proceedings, 48(1), 173-176.
https://doi.org/10.1016/j.transproceed.2015.12.023
Bhandari, A., Shah, P., Pandey, N. K., Nepal, R., & Sherchand, O. (2021). Anaemia among patients of heart failure in a tertiary care centre of Nepal: a descriptive cross-sectional study. JNMA: Journal of the Nepal Medical Association, 59(241), 833.
https://doi.org/10.31729/jnma.6486
Khan I, Mahmood H, Malik A, Ahmad S. Frequency of anemia and renal insufficiency in patients with heart failure admitted to a tertiary care hospital in Lahore, Pakistan. Annals of King Edward Medical University. 2009;15(3):158–63. doi:10.1590/s0066 782x2009000900011
Shrestha A, Wagle P, Bishwakarma R. Prevalence and spectrum of iron deficiency in heart failure patients at a tertiary cardiac centre. Journal of Advanced Practice in Cardiac Sciences. 2023;8(1):45–50
Mehta J, Singh V, Patel H. Anemia and heart failure: prevalence, pathophysiological mechanisms and clinical implications—a narrative review. Cardiology Research and Practice. 2022;2022:9341976. doi:10.1155/2022/9341976.
Bhuromal, S., Memon, F. F., Shaikh, M. A., & Kumar, S. (2022). Frequency of anemia in patients admitted with acute decompensated heart failure in tertiary care cardiac hospital. Journal of Pharmaceutical Research International, 28-34. https://doi.org/10.9734/jpri/2022/v34i39b36245
Ikama MS, Nsitou BM, Mongo NS, Kimbally Kaky G, Nkoua JL, Kocko I, et al. Anaemia in patients hospitalized for heart failure at Brazzaville University Hospital. Sante. 2012;22(1):114–21.
Rahu, Q. A., Soomro, M. K., Fareed, G., Kumar, J., Soomro, I. E., & Memon, S. H. (2023). Anemia with Red Cell Indices among Patients Suffering from Chronic Cardiac Failure Admitted at Tertiary Care Hospital. Annals of Punjab Medical College, 17(4), 591–595.
https://doi.org/10.29054/apmc/2023.1458
Khan, M. A., Khan, O., Khan, Q. A., & Khan, Z. A. (2025). Anaemia in Heart Failure Patients: is it Looked for and Treated? Indus Journal of Bioscience Research, 3(1), 856–861.
https://doi.org/10.70749/ijbr.v3i1.558
Tegene, E., Mohammed, A., Godebo, T., Desu, G., & Tadasa, E. (2025). Prevalence of anemia and associated factors in patients with heart failure admitted to Jimma university medical center. BMC Cardiovascular Disorders, 25(1).
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