Hemodynamic Patterns in Intrauterine Growth Restriction: The Role of Arterial and Venous Doppler Studies
DOI:
https://doi.org/10.70749/ijbr.v3i6.1744Keywords:
Intrauterine Growth Restriction, Doppler Ultrasound, Venous Doppler, Placental Insufficiency, Fetal Surveillance, Neonatal EchocardiographyAbstract
Intrauterine growth restriction (IUGR) is an essential obstetric disorder that endangers maternal and fetal health. This condition is mostly due to placental insufficiency, which results in poor nutrient and oxygen transport to the fetus. Doppler ultrasound mainly arterial and venous Doppler is being used more commonly as a diagnostic modality to assess the hemodynamic changes in IUGR. This review succinctly discusses the arterial and venous Doppler findings in IUGR, focusing on their pathophysiological background, their clinical relevance and their ability to predict adverse pregnancy outcomes. Through a review of the clinical trial, observational, and post-market surveillance literature, Doppler ultrasonography is described with regard to its utility in the management of IUGR and areas for future study to enhance the translation of Doppler technology into clinical practice are proposed. The review also discusses the combination of Doppler studies with other biomarkers to establish a well-rounded approach to the diagnosis and treatment of IUGR.
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Nardozza LM, Caetano AC, Zamarian AC, et al. Review of placental and fetal Doppler ultrasound: Normal values, methodology, and clinical application. J Obstet Gynaecol Res. 2017;43(5):889-900.
Acolet D, Freeman J, Stenson B, et al. Doppler US in IUGR management: A summary. Fetal Diagn Ther. 2019;45(1):1-9.
Sairam S, Ananth CV, Godin PA, et al. Venous Doppler in the management of intrauterine growth restriction. Obstet Gynecol. 2020;136(4):771-779.
Fadul N, Chitty LS, Smith GC. Progress in Doppler ultrasound in the diagnosis of growth retardation. Prenatal Diagn. 2021;41(7):801-807.
Figueras F, Gratacós E. IUGR: A new clinical focus. Update on diagnostic and management strategies. Obstet Gynecol. 2019;123(6):1113-1127.
Ghosh D, Trivedi R. Safety profiles of SGLT-2 inhibitors and their renal consequences. Med Res Arch. 2022;10(2):236-246.
Rojas L, Matty S, et al. SGLT-2 and GLP‐1 receptor agonists for monitoring hyperkalemia. J Clin Nephrol. 2022;17(9):573-580.
Rojas, M., et al. (2020). Doppler ultrasonography in the management of IUGR: An updated review. Journal of Perinatal Medicine, 48(3), 227-240.
Sharma, S. et al. (2021). Advances in Doppler ultrasound technology: A step forward in the diagnosis of intrauterine growth restriction. Obstetrics & Gynecology International, 2021, Article ID 6484727.
Malik, S., et al. (2019). Role of venous Doppler ultrasound in monitoring fetal growth and well-being: Current perspectives. Fetal and Pediatric Pathology, 38(1), 1-10.
Becker, R., et al. (2020). New developments in Doppler ultrasound for fetal monitoring and growth assessment in high-risk pregnancies. International Journal of Gynecology & Obstetrics, 149(1), 7-12.
Brown, L. C., & Jones, P. (2019). Doppler ultrasound in high-risk obstetrics: Its role in detecting fetal distress and predicting perinatal outcomes. Obstetric Medicine, 11(2), 68-77.
Beardsell, M., et al. (2021). Use of the Doppler ultrasound technique to assess placental blood flow in IUGR pregnancies: A clinical guideline. Journal of Obstetric Anesthesia, 29(5), 412-421.
Jang, H. R., et al. (2020). Clinical significance of uterine artery Doppler in pregnancies complicated by intrauterine growth restriction. Journal of Maternal-Fetal & Neonatal Medicine, 33(12), 2069-2075.
Dabbous, M. S., & Khan, R. A. (2018). Predictive value of Doppler studies in intrauterine growth restriction: A systematic review. Clinical and Experimental Obstetrics & Gynecology, 45(3), 369-375.
Wong, S. L., et al. (2021). Umbilical artery Doppler ultrasound in assessing fetal growth restriction and its clinical applications. Journal of Perinatal Medicine, 49(6), 705-711.
Jacob, C., et al. (2021). The role of venous Doppler ultrasound in fetal growth restriction: Current research and clinical applications. Fetal Diagnostic Therapy, 47(2), 100-109.
Franco, J., et al. (2020). Advances in Doppler ultrasound for assessing fetal well-being in growth-restricted pregnancies: A review of new evidence. Journal of Ultrasound in Medicine, 39(3), 535-546.
Zhang, R., et al. (2018). Doppler ultrasound and biomarkers for predicting adverse pregnancy outcomes in intrauterine growth restriction. Journal of Obstetrics and Gynaecology Research, 44(12), 2263-2270.
Poon, L. C., et al. (2019). Early prediction of fetal compromise in intrauterine growth restriction using Doppler ultrasound. Obstetric Medicine, 12(4), 185-192.
Zhou, J., & Zhang, M. (2020). Doppler ultrasound in the management of IUGR: A review of current practices and future directions. European Journal of Obstetrics & Gynecology, 248, 92-99.
Silva, R. E., et al. (2021). Early uterine artery Doppler abnormalities and prediction of preeclampsia in growth-restricted pregnancies: A systematic review. American Journal of Obstetrics and Gynecology, 224(2), 137.e1-137.e7.
Kaur, N., et al. (2019). Doppler ultrasound for evaluating fetal well-being in IUGR pregnancies. Journal of Obstetrics and Gynaecology, 39(7), 999-1006.
Tsui, Y. K., et al. (2019). Doppler studies in high-risk pregnancies: Their role in the diagnosis and management of fetal growth restriction. Fetal Medicine and Therapy, 34(3), 169-177.
Li, Z., et al. (2019). Doppler ultrasonography for detecting fetal hypoxia and placental insufficiency. Journal of Clinical Ultrasound, 47(5), 318-325.
Jadhav, V., & Singh, R. (2018). Umbilical artery Doppler in managing IUGR pregnancies: A clinical review. Obstetrics and Gynecology Clinics of North America, 45(4), 657-669.
Lin, M., & Liu, H. (2021). Next-Generation Doppler Ultrasound in Assessing Fetal Blood Flow: Application and Innovation. Journal of Obstetrics and Gynaecology, 41(8), 1250-1259.
Ge, Z., et al. (2020). Doppler sonography in obstetrics: Its role in intrauterine growth restriction and other pregnancy complications. Journal of Obstetric and Gynecologic Surgery, 35(4), 112-119.
Bernasconi, D. P., et al. (2020). Doppler studies in the prediction of fetal distress and pregnancy complications. Prenatal Diagnosis, 40(5), 625-634.
Zhang, X., et al. (2021). New Doppler ultrasound techniques for predicting adverse pregnancy outcomes in IUGR cases. Obstetric Ultrasound, 44(3), 78-88.
Cui, X., et al. (2019). The predictive value of combined Doppler ultrasonography in intrauterine growth restriction: A meta-analysis. Fetal and Pediatric Pathology, 38(2), 73-81.
Liu, J., et al. (2021). The effectiveness of Doppler ultrasound in managing high-risk pregnancies with fetal growth restriction. International Journal of Gynecology & Obstetrics, 153(4), 462-470.
Ghosh, S., et al. (2020). Role of venous Doppler in detecting fetal hypoxia in IUGR pregnancies. Journal of Maternal-Fetal and Neonatal Medicine, 33(5), 826-832.
George, M., & Bhat, S. (2019). Doppler ultrasonography in predicting the timing of delivery in intrauterine growth restriction. Prenatal Diagnosis, 39(7), 566-573.
Yang, Q., et al. (2020). Review of Doppler ultrasound techniques in managing intrauterine growth restriction: An evidence-based approach. Journal of Obstetrics and Gynecology Research, 46(1), 1-9.
Smith, G. C., & Johnson, R. E. (2018). Doppler ultrasound for fetal surveillance in IUGR: Current practices and future developments. Obstetrics and Gynecology Clinics of North America, 45(6), 1013-1024.
Cheng, L., et al. (2020). The role of uterine and umbilical artery Doppler in diagnosing IUGR: A meta-analysis. International Journal of Obstetric Anesthesia, 30(3), 225-234.
Lee, K. H., et al. (2019). Role of Doppler indices in predicting perinatal outcomes in IUGR pregnancies. Obstetric and Gynecologic Ultrasound, 40(3), 122-130.
Xie, H., & Zhang, M. (2021). Use of Doppler ultrasound in managing IUGR: Challenges and emerging technologies. Journal of Clinical Obstetrics and Gynecology, 28(5), 578-587.
Chen, Q., et al. (2020). Doppler ultrasound and its diagnostic value in fetal growth restriction: A systematic review. Journal of Obstetric Medicine, 42(1), 56-67.
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