Causes of Postpartum Haemorrhage Seen in Patients Referred to Jinnah Postgraduate Medical Center (JPMC)
DOI:
https://doi.org/10.70749/ijbr.v3i6.1891Keywords:
Postpartum hemorrhage (PPH), Risk factors, causes, primary PPH, Secondary PPHAbstract
Background and Aim: Postpartum hemorrhage (PPH) remains an important contributor to maternal illness and mortality, especially in developing countries. Prompt identity of its causes is necessary for timely management and improvement in maternal outcomes. Therefore, the present study aimed to determine the causes of postpartum hemorrhage in patients referred to Jinnah Postgraduate Medical Centre, Karachi. Patients and Methods: This cross-sectional study investigated 104 postpartum hemorrhage (primary or secondary) cases in the Obstetrics and Gynecology Department, Jinnah Postgraduate Medical Centre (JPMC), Karachi from March 2024 to March 2025. Patients referred from peripheral healthcare facilities either booked or unbooked cases, preterm and term deliveries, and inpatients were included. Data obtained from medical records, including demographic variables (age, marital status, parity, booking status), obstetrical history (gestational age, mode of delivery), type of PPH (primary or secondary), and specific causes (e.g., uterine atony, trauma, uterine rupture, placenta accreta spectrum, infection, uterine inversion, arteriovenous malformation, and coagulation disorders). SPSS version 26 used for data analysis. Results: The current study included 104 patients with postpartum hemorrhage; the most affected age group was 21–30 years 48 (46.2%) cases. The incidence of primary and secondary PPH was 96 (92.3%) and 8 (7.7%), respectively. Anemia was the most prevalent risk factor found in 26 (25%) cases followed by Prolonged Labor 12 (11.5%) and Eclampsia 8 (7.7%) cases. Atonic uterus emerged as the most prevalent cause of PPH, accounting for 73 (70.2%) cases. Traumatic PPH contributed to 20 (19.2%) cases and retained product of conception (RPOC) 11 (10.6%) cases. Of the total cases, 44 (42.3%) patients underwent surgical intervention whereas 60 (57.7%) were medically managed. Conclusion: Atonic uterus, identified as a major cause of postpartum hemorrhage (PPH), followed by traumatic and retained products of conception. These findings emphasize the need of prompt recognition and management of the atonic uterus, as well as effectively reducing the incidents and severity of PPH for trauma and incomplete placental expulsion.
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1. Nyloft LT, Sandven I, Stray Paderson B, Pettersen S et al. Risk factors for severe PPH: a case control study. BMC Pregnancy & Child birth. 2017; 17:17-27.
https://doi.org/10.1186/s12884-016-1217-0
2. Fukami T, Koga H, Goto M, Ando M, Matsuoka S, Tohyama A, Yamamoto H, Nakamura S, Koyanagi T, To Y, Kondo H. Incidence and risk factors for postpartum hemorrhage among transvaginal deliveries at a tertiary perinatal medical facility in Japan. PloS one. 2019 9;14(1):e0208873.
https://doi.org/10.1371/journal.pone.0208873
3. Sultana R, Manzoor S, Humayun S. Primary postpartum hemorrhage: risk factors, causes and maternal outcome. Journal of The Society of Obstetricians and Gynaecologists of Pakistan. 2020 29;10(1):40-6.
4. Gul F, Jabeen M, Heema. Frequency, causes and outcome of postpartum haemorrhage at Liaqat Memorial Hospital Kohat, Pakistan. Khyber Med Univ J 2018;10(2):90-94.
https://doi.org/10.35845/kmuj.2018.17512
5. Fatima N, Kubra K. Postpartum hemorrhage: Causes and outcome. J Surg Pakistan 2019; 24(1):28-33.
6. Sheikh L, Najmi N, Khalid U and Saleem T. Evaluation of compliance and outcomes of a management protocol for massive postpartum hemorrhage at a tertiary care hospital in Pakistan. BMC Pregnancy and Childbirth 2011, 11:28.
https://doi.org/10.1186/1471-2393-11-28
7. Khan JA, Zhu S, Wang X An overview on the cause and management of postpartum hemorrhage. Int J Cur Res Rev. 2019. 11(09). 01-06.
https://doi.org/10.31782/ijcrr.2019.0106
8. Sharma B, Sikka P, Jain V, Jain K, Bagga R, Suri V. Peripartum hysterectomy in a tertiary care hospital: Epidemiology and outcomes. J Anaesthesiol Clin Pharmacol. 2017;33(3):324-328.
https://doi.org/10.4103/joacp.joacp_380_16
9. Mazhar SB, Batool M, Batool M, Nazir A. Postpartum hemorrhage and its predisposing factors In WHO Multi-Country Survey on Maternal and Newborn Health, Pakistan.J. Soc. Obstet. Gynaecol. Pak.2018,8(2)104-1087.
10. Gora K, Depan A, Yadav K, Benwal D. Causes and management of post-partum haemorrhage at tertiary care centre, Rajasthan, India. Int J Reprod Contracept Obstet Gynecol 2019;8:2425-8.
https://doi.org/10.18203/2320-1770.ijrcog20192443
11. Tasneem A, Sirsam S, Shanbhag V. Clinical study of post-partumhaemorrhage from a teaching hospital in Maharashtra, India.Int J Reprod Contracept Obstet Gynecol. 2017; 6(6): 2366-2369.
https://doi.org/10.18203/2320-1770.ijrcog20172314
12. Cunningham FO Levenovo KJ, Bloorn SL, et al Obstetrical Haemorrhage, Williams Obstetrics. USA: McGraw-Hill Education. 2018;25:756.
13. Pooja G, Gupta RV, Dixit P. An Observational Study of Postpartum Hemorrhage at Tertiary health care Center of Central India. International Journal of Advanced Research. 2020:8(07):1236-1241.
https://doi.org/10.21474/ijar01/11391
14. Yousuf N, Farooq F, Yousuf K, Ali R, Yasmeen F, Ramzan S. Frequency, Management and Outcome of Postpartum Hemorrhage at a tertiary care Hospital. Journal of Muhammad Medical College. 2020;11(1):13-6.
https://doi.org/10.62118/jmmc.v11i1.118
15. Cadre S, Pate S, Gadre A. An overview of women with post-partum haemorrhage in, a tertiary care centre at capital of Madhya Pradesh, India. International Journal of Reproduction, Contraception ,Obstctrics and Gynecology. 20145;5(1):23-28.
https://doi.org/10.18203/2320-1770.ijrcog20151494
16. Tonge G, Burande A. A Retrospective study of cases of postpartum hemorrhage at tertiary health center. 1114lian Journal or Obstetric:4 and Gynaecology Research,. 2018;5(3):322-326.
https://doi.org/10.18231/2394-2754.2018.0074
17. Ekka AR. Prevalence and Risk Factors of Postpartum Hemorrhage in a Tertiary Care Hospital: An Observational Analysis. European Journal of Cardiovascular Medicine. 2025 Jan 18;15:210-5.
18. Betti T, Gouveia HG, Gasparin VA, Vieira LB, Strada JKR, Fagherazzi J. Prevalence of risk factors for primary postpartum hemorrhage in a university hospital. Rev Bras Enferm. 2023 Nov 27;76(5):e20220134.
https://doi.org/10.1590/0034-7167-2022-0134.
19. Butwick AJ, Ramachandran B, Hegde P, Riley ET, El-Sayed YY, Nelson LM. Risk Factors for Severe Postpartum Hemorrhage After Cesarean Delivery: Case-Control Studies. Anesth Analg. 2017 Aug;125(2):523-532.
https://doi.org/10.1213/ANE.0000000000001962.
20. Nigussie J, Girma B, Molla A, Tamir T, Tilahun R. Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis. Reprod Health. 2022 Mar 9;19(1):63.
https://doi.org/10.1186/s12978-022-01360-7.
21. Bakhtiari AF, Zahra T, Kamal A, Shahid A, Mushtaq F, Rasool S. Prevalence of Primary Post-partum Haemorrhage and Factors Related to it among Women Delivered in a Tertiary Care Hospital.
https://doi.org/10.37018/jfjmu/9410
22. Yang Y, Shao Y, Chen H, Guo X, Liang Y, Wang Y, Zhao Y. Characteristics and treatment for severe postpartum haemorrhage in different midwifery hospitals in one district of Beijing in China: an institution-based, retrospective cohort study. BMJ open. 2024 Apr 1;14(4):e077709.
https://doi.org/10.1136/bmjopen-2023-077709
23. Ravella Sowjanya DP, Nisha K, Thokala S. A Study on Postpartum Haemorrhage Leading to Maternal Mortality and Morbidity among Emergency Admissions at Tertiary Hospital, AP. Journal of Cardiovascular Disease Research. 2024 Dec 31;15(12):201-12.
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