Frequency of Hyponatremia in Intensive Care Unit
DOI:
https://doi.org/10.70749/ijbr.v3i6.2149Keywords:
Hyponatremia, Frequency, Intensive care unitAbstract
Background: Hyponatremia is often a common and overlooked complication in ICU. There is scarcity of data reporting in our setup. We aimed to find the frequency of hyponatremia in ICU patients. Methodology: It was a cross-sectional study conducted at Ghurki Trust Teaching Hospital, for a duration of 6 months in intensive care unit of the hospital. 150 patients were included as per inclusion and exclusion criteria. All the data about age, gender and co-morbidities was recorded on a Performa. The presence or absence of hyponatremia was also noted. All the collected data. Results: The mean age of the patient was 62.06 ± 9.80 years.100 (66.7%) were male and 50 (33.3%) were females. The frequency of hyponatremia came out to be 24% (36 patients). Hyponatremia was significantly associated with age greater than 60 years but was not associated with diabetes and hypertension. Conclusion: The frequency of hyponatremia in ICU patients is significantly high. Its prevalence is related with age of the patient. A larger multicenter study to explore other contributing factors is recommended.
Downloads
References
1. Arzhan S, Roumelioti M-E, Litvinovich I, Bologa CG, Myers OB, Unruh ML. Hypernatremia in Hospitalized Patients: A Large Population-Based Study. Kidney360. 2022;3(7):1144-57.
https://doi.org/10.34067/kid.0000702022
2. Hyndman KA, Speed JS, Mendoza LD, Allan JM, Colson J, Sedaka R, et al. Fluid-electrolyte homeostasis requires histone deacetylase function. JCI insight. 2020;5(16).
https://doi.org/10.1172/jci.insight.137792
3. Pirklbauer M. Hemodialysis treatment in patients with severe electrolyte disorders: Management of hyperkalemia and hyponatremia. Hemodialysis international International Symposium on Home Hemodialysis. 2020;24(3):282-9.
https://doi.org/10.1111/hdi.12845
4. Friedman B, Cirulli J. Hyponatremia in critical care patients: frequency, outcome, characteristics, and treatment with the vasopressin V2-receptor antagonist tolvaptan. J Crit Care. 2013;28(2):219.e1-12.
https://doi.org/10.1016/j.jcrc.2012.06.001
5. Parajuli S, Tiwari S, Gupta SK, Shakya YM, Shakya YL. Hyponatremia in Patients Admitted to Intensive Care Unit of a Tertiary Center: A Descriptive Cross-sectional Study. JNMA; journal of the Nepal Medical Association. 2022;60(255):935-8.
https://doi.org/10.31729/jnma.7123
6. Khan H, Malik F, Khan Y, Zada S, Ilahi N, Sohail M, et al. Frequency of hyponatremia and its common complications among patients with hepatic encephalopathy. Int J Biosci. 2017;10(1):195-201.
https://doi.org/10.12692/ijb/10.1.195-201
7. Saleem M, Khattak AL, Ayaz SB, Raza Q, Anjum N, Raza SA. Frequency of hyponatremia in patients with acute cerebrovascular accidents presenting at combined military hospital Peshawar. Pakistan Armed Forces Medical Journal. 2020;70(2):297-301.
8. Malabu U, Porter D, Vangaveti V, Kazi M, Kennedy R. Prevalence of hyponatremia in acute medical admissions in tropical Asia Pacific Australia. Asian Pacific journal of tropical medicine. 2014;7:40-3.
https://doi.org/10.1016/s1995-7645(13)60189-3
9. Sim JK, Ko RE, Na SJ, Suh GY, Jeon K. Intensive care unit-acquired hyponatremia in critically ill medical patients. Journal of Translational Medicine. 2020 Jul 2;18(1):268.
https://doi.org/10.1186/s12967-020-02443-4
10. Patil S, Mukherji A, Shetty A. Incidence of hyponatremia in critically ill patients in intensive care unit: observational study. International Journal of Dental and Medical Specialty. 2016;3(1and2):12-5.
https://doi.org/10.5958/2394-4196.2016.00004.2
11. Debnath P, Debbarma RK, Debbarma D, Sarkar S. Study of Hyponatremia among Patients Admitted In Icu Of A Tertiary Care Hospital. IOSR J Dent Med Sci. 2021;20(8):18-23.
12. Babaliche P, Madnani S, Kamat S. Clinical profile of patients admitted with hyponatremia in the medical intensive care unit. Indian journal of critical care medicine: peer-reviewed, official publication of Indian Society of Critical Care Medicine. 2017 Dec;21(12):819.
https://doi.org/10.4103/ijccm.ijccm_257_17
13. Sim JK, Ko RE, Na SJ, Suh GY, Jeon K. Intensive care unit-acquired hyponatremia in critically ill medical patients. Journal of Translational Medicine. 2020 Jul 2;18(1):268.
https://doi.org/10.1186/s12967-020-02443-4
14. Otterness K, Singer AJ, Thode Jr HC, Peacock WF. Hyponatremia and hypernatremia in the emergency department: severity and outcomes. Clinical and experimental emergency medicine. 2023 Jan 30;10(2):172.
https://doi.org/10.15441/ceem.22.380
15. Guruswamy NT, Khan H, Hegde P. Correlation of hyponatremia in children presenting with acute lower respiratory tract infection in a tertiary care hospital. Int J Recent Trends Sci Technol. 2014;12:631-4.
16. Grim CC, Termorshuizen F, Bosman RJ, Cremer OL, Meinders AJ, Nijsten MW, Pickkers P, de Man AM, Schultz MJ, van Vliet P, Weigel JD. Association between an increase in serum sodium and in-hospital mortality in critically ill patients. Critical care medicine. 2021 Dec 1;49(12):2070-9.
https://doi.org/10.1097/ccm.0000000000005173
17. Itoh J, Aoki Y, Omoto M, Katsuragawa T, Mimuro S, Nakajima Y. Association Between Early Hyponatremia and Clinical Outcomes in Critically Ill Patients: A Retrospective Cohort Study. Cureus. 2024 Mar 14;16(3).
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Indus Journal of Bioscience Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
