Diagnostic Accuracy of Magnetic Resonance Imaging (MRI) in Diagnosing Anterior Cruciate Ligament Tear (ACL) Taking Arthroscopy as Gold Standard

Authors

  • Namra Tanveer Department of Diagnostic Radiology, Combined Military Hospital (CMH), Lahore, Punjab, Pakistan.
  • Tariq Mahmud Mirza Department of Diagnostic Radiology, Combined Military Hospital (CMH), Lahore, Punjab, Pakistan.
  • Ayesha Faiz Department of Diagnostic Radiology, Combined Military Hospital (CMH), Lahore, Punjab, Pakistan.
  • Fatima Shakeel Department of Diagnostic Radiology, Combined Military Hospital (CMH), Lahore, Punjab, Pakistan.
  • Maheen Asad Department of Diagnostic Radiology, Combined Military Hospital (CMH), Lahore, Punjab, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i6.2687

Keywords:

Anterior Cruciate Ligament, Arthroscopy, Diagnostic Accuracy, Knee Injuries, Magnetic Resonance Imaging.

Abstract

Background: Anterior cruciate ligament tear is a frequent cause of post traumatic knee instability. Arthroscopy is the reference standard but is invasive, whereas magnetic resonance imaging is widely used as a noninvasive alternative. Aim: To determine the diagnostic accuracy of magnetic resonance imaging in diagnosing anterior cruciate ligament tear, using arthroscopy as the gold standard. Materials and Methods: A cross sectional survey was conducted in the Department of Diagnostic Radiology, Combined Military Hospital Lahore, over six months (October 2024 to March 2025). Non probability consecutive sampling enrolled 142 patients aged 16 to 55 years with recent knee trauma within two months and positive anterior drawer and Lachman tests. Magnetic resonance imaging was performed on a 0.5 tesla system using multiplanar T1 weighted, T2 weighted, proton density fat saturated, and short tau inversion recovery sequences. Anterior cruciate ligament tear on magnetic resonance imaging was defined as non visualization or disruption with multi fragmented appearance. Arthroscopy was performed under general anaesthesia by a blinded surgical team and tear was defined as disruption of one third or more ligament fibers. A 2 by 2 table was used to compute sensitivity, specificity, predictive values, and diagnostic accuracy. Results: Mean age was 29.4 ± 8.7 years and mean body mass index was 25.6 ± 3.9 kg/m²; 98 (69.0%) participants were male. Right knee involvement was seen in 80 (56.3%). Sports injuries accounted for 65 (45.8%) cases. Arthroscopy confirmed tears in 89 (62.7%). Magnetic resonance imaging yielded 82 true positives, 46 true negatives, 7 false positives, and 7 false negatives, giving sensitivity 92.1%, specificity 86.8%, PPV 92.1%, NPV 86.8%, and accuracy 90.1%. Conclusion: Magnetic resonance imaging showed high diagnostic accuracy for anterior cruciate ligament tear compared with arthroscopy in clinically suspected injuries.

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References

1. Soni, M. K., Shamim, S., Verma, A., & Singh, G. K. (2023). A comparative study of anterior cruciate ligament reconstruction versus conservative treatment. Cureus.

https://doi.org/10.7759/cureus.49148

2. Mancino, F., Gabr, A., Plastow, R., & Haddad, F. S. (2023). Anterior cruciate ligament injuries in female athletes. The Bone & Joint Journal, 105-B(10), 1033-1037.

https://doi.org/10.1302/0301-620x.105b10.bjj-2023-0881.r1

3. Beaulieu, M. L., Ashton-Miller, J. A., & Wojtys, E. M. (2021). Loading mechanisms of the anterior cruciate ligament. Sports Biomechanics, 22(1), 1-29.

https://doi.org/10.1080/14763141.2021.1916578

4. Mohammed, E. R., Metwally, N. A., & Elaidy, A. A. (2019). Role of magnetic resonance imaging in assessment of anterior cruciate ligament post-grafting cases in terms of Graft integrity and complications. The Egyptian Journal of Hospital Medicine, 76(2), 3446-3453.

https://doi.org/10.21608/ejhm.2019.37930

5. AHMAD, M. W., Saeed, A., & Rashid, N. (2024). Diagnostic accuracy of magnetic resonance imaging (MRI) knee in detecting anterior cruciate ligament (ACL) tears assuming arthroscopy as gold standard. Journal of Fatima Jinnah Medical University, 18(3), 130-133.

https://doi.org/10.37018/bksk6936

6. Ahmed, A., Razzaque, M. A., Kaleem, M., Zaman, A. U., Akram, R., & Javed, S. (2017). Diagnostic accuracy of magnetic resonance imaging in detecting anterior cruciate ligament injuries. Medical Journal of Indonesia, 26(3), 218-23.

https://doi.org/10.13181/mji.v26i3.1873

7. Khandelwal, K., Chaturvedi, V., Mishra, V., & Khandelwal, G. (2018). Diagnostic accuracy of MRI knee in reference to arthroscopy in meniscal and anterior cruciate ligament injuries. The Egyptian Journal of Radiology and Nuclear Medicine, 49(1), 138-145.

https://doi.org/10.1016/j.ejrnm.2017.12.003

8. Shibayama, Y., Hirose, T., Sugi, A., Mizushima, E., Watanabe, Y., Tomii, R., Iba, K., & Yamashita, T. (2022). Diagnostic accuracy of magnetic resonance imaging for partial tears of the long head of the biceps tendon in patients with rotator cuff tears. JSES International, 6(4), 638-642.

https://doi.org/10.1016/j.jseint.2022.03.001

9. Fotiadou, A. N., Vlychou, M., Papadopoulos, P., Karataglis, D. S., Palladas, P., & Fezoulidis, I. V. (2008). Ultrasonography of symptomatic rotator cuff tears compared with MR imaging and surgery. European Journal of Radiology, 68(1), 174-179.

https://doi.org/10.1016/j.ejrad.2007.11.002

10. Hameed Khan, R., Iqbal, J., Ahmad, A., & Kamal, S. (2025). Diagnostic accuracy of magnetic resonance imaging knee in diagnosis of anterior cruciate ligament tear taking arthroscopy as gold standard. Indus Journal of Bioscience Research, 3(4), 805-810.

https://doi.org/10.70749/ijbr.v3i4.1108

11. Zhao, M., Zhou, Y., Chang, J., Hu, J., Liu, H., Wang, S., Si, D., Yuan, Y., & Li, H. (2020). The accuracy of MRI in the diagnosis of anterior cruciate ligament injury. Annals of Translational Medicine, 8(24), 1657-1657.

https://doi.org/10.21037/atm-20-7391

12. Li, K., Du, J., Huang, L., Ni, L., Liu, T., & Yang, H. (2017). The diagnostic accuracy of magnetic resonance imaging for anterior cruciate ligament injury in comparison to arthroscopy: A meta-analysis. Scientific Reports, 7(1).

https://doi.org/10.1038/s41598-017-08133-4

13. Sampson, M., Jackson, M., Moran, C., Moran, R., Eustace, S., & Shine, S. (2008). Three Tesla MRI for the diagnosis of meniscal and anterior cruciate ligament pathology: A comparison to arthroscopic findings. Clinical Radiology, 63(10), 1106-1111.

https://doi.org/10.1016/j.crad.2008.04.008

14. Koch, J. E., Ben-Elyahu, R., Khateeb, B., Ringart, M., Nyska, M., Ohana, N., Mann, G., & Hetsroni, I. (2021). Accuracy measures of 1.5-tesla MRI for the diagnosis of ACL, meniscus and articular knee cartilage damage and characteristics of false negative lesions: A level III prognostic study. BMC Musculoskeletal Disorders, 22(1).

https://doi.org/10.1186/s12891-021-04011-3

15. Kumbar, V., Tonne, V., & Kumar, A. (2018). Correlation of magnetic resonance imaging and arthroscopic findings in meniscal and anterior cruciate ligament injuries. MedPulse International Journal of Radiology, 5(1), 05-08.

https://doi.org/10.26611/1013512

16. Aziz, M., Sadaf Aziz, Tariq, A., Khan, Y., Atif Latif, & Munazzah Aziz. (2024). Diagnostic accuracy of magnetic resonance imaging in diagnosing urinary bladder cancer, taking histopathology as gold standard. Pakistan Armed Forces Medical Journal, 74(SUPPL-2), S226-S230.

https://doi.org/10.51253/pafmj.v74isuppl-2.10849

17. Phelan, N., Rowland, P., Galvin, R., & O’Byrne, J. M. (2015). A systematic review and meta-analysis of the diagnostic accuracy of MRI for suspected ACL and meniscal tears of the knee. Knee Surgery, Sports Traumatology, Arthroscopy, 24(5), 1525-1539.

https://doi.org/10.1007/s00167-015-3861-8

18. Javaid, A., Anam, W., Ullah, H., Afzal, T., Mahmood, R., & Salah ud din Balooch. (2023). Diagnostic accuracy of magnetic resonance imaging (MRI) in the detection of anterior cruciate ligament (ACL) tear, keeping Arthroscopic findings as gold standard. Pakistan Armed Forces Medical Journal, 73(5), 1249-1252.

https://doi.org/10.51253/pafmj.v73i5.7687

19. Ahmed, Z. T., Khan, N. H., Bilal, S., Ameer, S., Tanveer, F., & Tanveer, M. (2020). Diagnostic accuracy of magnetic resonance imaging for detection of anterior cruciate ligament tears taking arthroscopy as gold standard. In Medical Forum Monthly (Vol. 31, No. 3).

https://medicalforummonthly.com/index.php/mfm/article/view/2224

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Published

2025-06-30

How to Cite

Tanveer, N., Mirza, T. M., Faiz, A., Shakeel, F., & Asad, M. (2025). Diagnostic Accuracy of Magnetic Resonance Imaging (MRI) in Diagnosing Anterior Cruciate Ligament Tear (ACL) Taking Arthroscopy as Gold Standard. Indus Journal of Bioscience Research, 3(6), 1248-1252. https://doi.org/10.70749/ijbr.v3i6.2687