Frequency and Outcome in Patients Presenting with NSTEMI Undergoing PCI for MV Coronary Artery Disease in Index Hospitalization at Tertiary Care Hospital, Karach
DOI:
https://doi.org/10.70749/ijbr.v3i6.2721Keywords:
NSTEMI, Multivessel Coronary Artery Disease, Percutaneous Coronary Intervention, In-hospital Mortality, Cardiovascular Risk Factors.Abstract
Background: Multivessel coronary artery disease (MVD) in patients with Non-ST Elevation Myocardial Infarction (NSTEMI) presents a significant clinical challenge, influencing treatment decisions and patient outcomes. Understanding the frequency of MVD and its impact on in-hospital mortality can help guide more effective management strategies. Objective: To determine the frequency and outcome in patients presenting with NSTEMI undergoing PCI for MV coronary artery disease in index hospitalization at Tertiary Care Hospital, Karachi. Methods: This retrospective, observational study analyzed 133 patients diagnosed with NSTEMI who underwent PCI. Baseline characteristics, comorbidities, lifestyle factors, and socioeconomic status were compared between patients with and without MVD. The primary outcomes were the frequency of MVD and in-hospital mortality. Statistical analyses assessed associations between patient characteristics and outcomes. Results: Multivessel disease was present in 36.1% of patients. Significant differences were observed in residence status (P = 0.01), smoking (P = 0.01), hypertension (P = 0.04), dyslipidemia (P = 0.01), family history of coronary artery disease (P = 0.01), and income levels (P = 0.01) between the MVD and non-MVD groups. In-hospital mortality was 20.3%, with a higher incidence among MVD patients. Conclusion: NSTEMI patients with MVD face a higher risk of in-hospital mortality, particularly those from rural areas, smokers, and lower-income groups. Early diagnosis, targeted prevention, and optimized treatment strategies are crucial for improving outcomes. Further research is needed to assess long-term effects and refine management approaches for high-risk patients.
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