Comparison of the Mean Duration of Postoperative Analgesia of Epidural Dexmedetomidine and Fentanyl as an Adjuvant to 0.2% Ropivacaine in Elective Abdominal Surgeries

Authors

  • Affan Ahmad Khan Department of Anesthesia & Critical Care, Doctors Hospital and Medical Centre Lahore, Pakistan
  • Khawar Ali Department of Anesthesia & Critical Care, Doctors Hospital and Medical Centre Lahore, Pakistan
  • Sami Ur Rehman Department of Anesthesia & Critical Care, Doctors Hospital and Medical Centre Lahore, Pakistan
  • Asif Ali Department of Anesthesia & Critical Care, Doctors Hospital and Medical Centre Lahore, Pakistan
  • Maria Adrees Department of Anesthesia & Critical Care, Doctors Hospital and Medical Centre Lahore, Pakistan

DOI:

https://doi.org/10.70749/ijbr.v3i6.2877

Keywords:

Abdominal surgeries, dexmedetomidine, fentanyl, postoperative analgesia

Abstract

Objectives: To compare the mean duration of postoperative analgesia of epidural dexmedetomidine and fentanyl as an adjuvant to 0.2% ropivacaine in elective abdominal surgeries. Study Design: Randomized Controlled Trial. Settings: Department of Anaesthesia, Doctors Hospital & Medical Centre, Lahore. Duration of Study: June 2024 to December 2024. Materials & Methods: Patients who were between the ages of 20 and 60 years, had ASA I and II, and were having major abdominal surgery were included. Patients with coagulopathy, significant cardiovascular disease, renal failure, history of allergy to local anesthetics or alpha-2 adrenergic agonists were excluded. Following that, these patients were split into two groups of thirty each at random using the lottery method. Group I-RF (Ropivaciain 0.2% 9 ml with fentanyl 1 μg/kg). Group II-RD (Ropivaciain 0.2% 9 ml with dexmedetomidine 1 μg/kg). The length of analgesia was recorded. The result was displayed as the mean. Results: The mean age of patients in groups I and II was 40.93 ± 9.12 and 41.43 ± 8.33 years, respectively. 162.39 ± 10.53 cm was the average height. The mean weight was 72.68 ± 7.53 kg. The mean BMI was 27.75 ± 3.93 kg/m2. The average surgical time for patients in groups I and II was 36.72 ± 6.12 minutes and 39.19 ± 7.28 minutes, respectively. The duration of postoperative analgesia in this trial was 539.89 ± 49.83 in group II and 1362.46 ± 51.15 in group I. Conclusion: According to this study, low doses of ropivacaine (0.2%) combined with dexmedetomidine and fentanyl give efficient and long-lasting pain relief without significantly impairing motor function.

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References

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Published

2025-06-30

How to Cite

Khan, A. A., Ali, K., Sami Ur Rehman, Ali, A., & Adrees, M. (2025). Comparison of the Mean Duration of Postoperative Analgesia of Epidural Dexmedetomidine and Fentanyl as an Adjuvant to 0.2% Ropivacaine in Elective Abdominal Surgeries. Indus Journal of Bioscience Research, 3(6), 1321-1325. https://doi.org/10.70749/ijbr.v3i6.2877