Radiological Comparison of X-ray and Computed Tomography in Diagnosing Fungal Sinusitis and Nasal Polyps

Authors

  • Kinzul Eman Department of Radiological Sciences & Medical Imaging Technology (DRS&MIT), Faculty of Allied Health Sciences, Superior University, Lahore, Punjab, Pakistan.
  • Emaan Rasheed Department of Radiological Sciences & Medical Imaging Technology (DRS&MIT), Faculty of Allied Health Sciences, Superior University, Lahore, Punjab, Pakistan.
  • Loqman Shah Lecturer, Medical Imaging Technology, Department of Radiological Sciences & Medical Imaging Technology, Faculty of Allied Health Sciences, Northern University, Nowshera, KP, Pakistan.
  • Ali Noman Department of Radiological Sciences & Medical Imaging Technology (DRS&MIT), Faculty of Allied Health Sciences, Superior University, Lahore, Punjab, Pakistan.
  • Muhammad Yousaf Department of Radiological Sciences & Medical Imaging Technology (DRS&MIT), Faculty of Allied Health Sciences, Superior University, Lahore, Punjab, Pakistan.
  • Areeba Tariq Department of Radiological Sciences & Medical Imaging Technology (DRS&MIT), Faculty of Allied Health Sciences, Superior University, Lahore, Punjab, Pakistan.
  • Noman Hameed Department of Radiological Sciences & Medical Imaging Technology (DRS&MIT), Faculty of Allied Health Sciences, Superior University, Lahore, Punjab, Pakistan.
  • Rimsha Riaz Department of Radiological Sciences & Medical Imaging Technology (DRS&MIT), Faculty of Allied Health Sciences, Superior University, Lahore, Punjab, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v4i4.3027

Keywords:

Radiological Comparison, Diagnosis, Fungal Sinusitis, Nasal Polyps, HRCT, X-ray, Diagnostic Accuracy.

Abstract

Introduction: Sinonasal diseases, mainly fungal sinusitis and nasal polyps, are found in a large percentage of chronic rhinosinusitis and have an important impact on patient quality of life. Early management and prevention of complications depend on accurate radiological diagnosis. Plain X-ray of Paranasal Sinuses (PNS) is commonly made more due to availability, being relatively less expensive; the Computed Tomography (CT) provides better anatomic characterization and is the basis of comparison for sino-nasal assessment. Objective: To evaluate radiological comparison of X-Ray and Computed Tomography in diagnosing Fungal Sinusitis and Nasal Polyps. Methodology: The study was a cross-sectional analytical study comprises of 60 patients of both sexes male/female between 12 to70 years suspected with fungal sinusitis or nasal polyp are included. Both X-ray PNS and CT-PNS were performed in all subjects. Results of imaging were correlated with endoscopy and histopathological diagnosis (gold standard). SPSS version 26 was used to measure sensitivity, specificity, PPV, NPV and the diagnostic accuracy. Results: The diagnosis of fungal sinusitis was made in 46.7% patients, and nasal polyps in 36.7%. X-ray had marginal sensitivity (64.3%) and specificity (70.8%), with overall accuracy of 67.5 %. On CT, the sensitivity and specificity were significantly higher (92.9% and 90.9%, respectively) with a diagnostic accuracy of 91.7% (p < 0.001). CT efficiently demonstrated typical signs including heterogeneous opacity, hyper attenuation foci, double-density sign and bone erosion. Conclusion: CT scan is far more accurate than X-ray in the diagnosis of fungal sinusitis and its distinction from nasal polyps. While X-ray might be used as a primary screening modality, CT is the optimal choice for final diagnosis and surgical planning.

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References

1. Hussein, A. O., Ahmed, B. H., Omer, M. A. A., Manafal, M. F., & Elhaj, A. B. (2014). Assessment of clinical, X-Ray and CT in diagnosis of paranasal sinus diseases. Int J of Sci Res, 3, 7-11.

2. Chaaban, M. R., Walsh, E. M., & Woodworth, B. A. (2013). Epidemiology and differential diagnosis of nasal polyps. American Journal of Rhinology & Allergy, 27(6), 473-478.

https://doi.org/10.2500/ajra.2013.27.3981

3. Drake-Lee, A. (2004). Nasal polyps. Hospital Medicine, 65(5), 264-267.

https://doi.org/10.12968/hosp.2004.65.5.13699

4. Varshney, H., Varshney, J., Biswas, S., & Ghosh, S. K. (2015). Importance of CT scan of Paranasal sinuses in the evaluation of the anatomical findings in patients suffering from Sinonasal polyposis. Indian Journal of Otolaryngology and Head & Neck Surgery, 68(2), 167-172.

https://doi.org/10.1007/s12070-015-0827-6

5. Drake-Lee AB (1997) Nasal polyps. In: Kerr AG, Mackay IS, Bull TR (eds) Scott-Brown’s Otolaryngology, Vol. 4: Rhinology 6th edn. Butterworth-Heinemann, Oxford 4/10/1–16.

6. Fokkens, W. J., Lund, V. J., Hopkins, C., Hellings, P. W., Kern, R., Reitsma, S., ... & Witterick, I. (2020). European position paper on rhinosinusitis and nasal polyps 2020. Rhinology, 58(Suppl S29), 1-464.

7. Fung, M., Babik, J., Humphreys, I. M., & Davis, G. E. (2019). Diagnosis and treatment of acute invasive fungal sinusitis in cancer and transplant patients. Current Infectious Disease Reports, 21(12).

https://doi.org/10.1007/s11908-019-0707-4

8. Cha, C., Chen, W., Wang, Y., Wu, S., Chiu, T., Wu, C., Wee, Y., Wang, C., Yang, Y., & Luo, S. (2023). Comparison of fungal and non-fungal rhinosinusitis by culture-based analysis. Journal of Personalized Medicine, 13(9), 1368.

https://doi.org/10.3390/jpm13091368

9. Bent, J. P., & Kuhn, F. A. (1994). Diagnosis of allergic fungal sinusitis. Otolaryngology–Head and Neck Surgery, 111(5), 580-588.

https://doi.org/10.1177/019459989411100508

10. Rosenfeld, R. M., Piccirillo, J. F., Chandrasekhar, S. S., Brook, I., Ashok Kumar, K., Kramper, M., Orlandi, R. R., Palmer, J. N., Patel, Z. M., Peters, A., Walsh, S. A., & Corrigan, M. D. (2015). Clinical practice guideline (Update): Adult sinusitis. Otolaryngology–Head and Neck Surgery, 152(S2).

https://doi.org/10.1177/0194599815572097

11. Lund, V. (2013). Anatomy, anatomy, anatomy...... Rhinology journal, 51(4), 289-290.

https://doi.org/10.4193/rhine514

12. Khullar, T., Kumar, J., Sindhu, D., Garg, A., & Meher, R. (2022). CT imaging features in acute invasive fungal rhinosinusitis- Recalling the oblivion in the COVID era. Current Problems in Diagnostic Radiology, 51(5), 798-805.

https://doi.org/10.1067/j.cpradiol.2022.02.001

13. Rao, U. S., & Sandeep, V. (2016). Clinical and radiological study of antrochoanal polyps. Headache, 18, 10.

14. Michaels, L. (1987). The normal nose and Paranasal sinuses. Ear, Nose and Throat Histopathology, 131-136.

https://doi.org/10.1007/978-1-4471-3332-2_12

15. Mukherji, S. K., Figueroa, R. E., Ginsberg, L. E., Zeifer, B. A., Marple, B. F., Alley, J. G., Cooper, L. L., Nemzek, W. R., Yousem, D. M., Jones, K. R., Kupferberg, S. B., & Castillo, M. (1998). Allergic fungal sinusitis: CT findings. Radiology, 207(2), 417-422.

https://doi.org/10.1148/radiology.207.2.9577490

16. Adil, R., Qayyum, A., & Qayyum, A. (2011). Correaltion of X rays and computed tomography in paranasal sinus diseases. Pak Armed Forces Med J, 61(3), 1-6.

17. Kayalioglu, G., Oyar, O., & Govsa, F. (2000). Nasal cavity and paranasal sinus bony variations: a computed tomographic study. Rhinology, 38(3), 108-113.

18. Kurokawa M, Sone M, Kitani Y, et al. Invasive fungal rhinosinusitis in the head and neck. RadioGraphics. 2022;42(2): E1-E19.

https://doi.org/10.1148/rg.220059

19. Chen A, Judson BL, Prasad ML, et al. Imaging features of invasive fungal rhinosinusitis. Can Assoc Radiol J. 2024;75(4):584-593

https://doi.org/10.1177/08465371241227424

20. Iqbal J, Shah SA, Tariq M, et al. Diagnostic accuracy of CT scan in diagnosing paranasal fungal sinusitis using histopathology as gold standard. J Coll Physicians Surg Pak. 2017; 27(5):300-303.

21. Naz N, Khan S, Ahmad I. Diagnostic accuracy of CT in fungal sinusitis and extent mapping. Ann Pak Inst Med Sci. 2016;12(2):61-65.

22. Wajih-Ud-Din Shinwari, Sadaf Raffat, Nighat Qamer Mustafa, and Azmatullah Khan Uzair Mushahid. "Prevalence of Fungal Rhinosinusitis in Patients Presenting with Nasal Polyps." Pakistan Journal of Medical & Health Sciences 16.09 (2022): 141-143.

https://doi.org/10.53350/pjmhs22169141

23. Khandedia, M. V., Bhardava, V. H., & Sarda, A. (2019). Evaluation of Paranasal Sinus Lesions through Plain X-rays and CT-Scan-A Descriptive Study.

http://14.139.121.113:8080/jspui/handle/123456789/712

24. Mafee, M. F., Farid, N., & Lim, W. Y. (2014). Imaging of the paranasal sinuses: plain-film radiography, Computed Tomography, and Magnetic Resonance Imaging. In Diseases of the Sinuses: A Comprehensive Textbook of Diagnosis and Treatment (pp. 295-322). New York, NY: Springer New York.

https://doi.org/10.1007/978-1-4939-0265-1_17

25. DelGaudio, J. M., Swain, R. E., Muller, S., & Hudgins, P. A. (2003). Computed tomographic findings in patients with invasive fungal sinusitis. Archives of Otolaryngology–Head & Neck Surgery, 129(2), 236-240.

https://doi.org/10.1001/archotol.129.2.236

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Published

2026-04-30

How to Cite

Eman, K., Rasheed, E., Shah, L., Noman, A., Muhammad Yousaf, Tariq, A., Hameed, N., & Riaz, R. (2026). Radiological Comparison of X-ray and Computed Tomography in Diagnosing Fungal Sinusitis and Nasal Polyps. Indus Journal of Bioscience Research, 4(4), 1-7. https://doi.org/10.70749/ijbr.v4i4.3027