Prevalance of HIV in Children with Severe Acute Malnutrition Admitted in Children Hospital PIMS
DOI:
https://doi.org/10.70749/ijbr.v3i2.569Keywords:
HIV, Children, Severe Acute MalnutritionAbstract
Background: Malnutrition contributes to about half of the mortality in children. HIV infection in children suffering from severe acute malnutrition (SAM) is a major health concern, especially in areas where both illnesses are prevalent. HIV and malnutrition have a synergistic effect on the immune system and general health, increasing risk of death and major complications. Our study focuses on finding prevalence of HIV infection in children admitted with severe acute malnutrition in a tertiary care hospital in Pakistan. Methodology: After taking informed consent from parents/guardians 140 children aged 6month to 5 years admitted with SAM were enrolled. After counselling of parents regarding HIV testing and written consent patients were tested for HIV via rapid HIV antibody test. If a child was found to be positive for HIV their parents were tested for HIV and the child registered in HIV center for management. The demographic data, HIV test results and anthropometric measurements of patients were entered in a preformed performa and data analyzed using SPSS 27. Results: In our study, 6 patients (4.3%) out of the 140 children admitted with severe acute malnutrition, had HIV. All SAM patients with HIV had a vertical HIV transmission pathway. Compared to the overall HIV incidence in Pakistan, the prevalence of HIV among children with SAM is significantly higher. Conclusion: Children who suffer from severe acute malnutrition are far more likely to be HIV-positive, this necessitates routine HIV screening.
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Asim, M., & Nawaz, Y. (2018). Child malnutrition in Pakistan: Evidence from literature. Children, 5(5), 60. https://doi.org/10.3390/children5050060
WHO. (2024). Malnutrition. Www.who.int. https://www.who.int/health-topics/malnutrition#tab=tab_2
WHO. (2013). Guideline: updates on the management of severe acute malnutrition in infants and children. Www.who.int. https://www.who.int/publications/i/item/9789241506328
World Health Organization. (2024, July 22). HIV and AIDS. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/hiv-aids
Treatment and care in children and adolescents. (2024). Www.who.int. https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/hiv/treatment/treatment-and-care-in-children-and-adolescents
UNICEF. (2020, November 30). Reimagining a resilient HIV response for children, adolescents and pregnant women living with HIV . UNICEF DATA. https://data.unicef.org/resources/world-aids-day-report-2020/
Mir, F., Mahmood, F., Siddiqui, A. R., Baqi, S., Abidi, S. H., Kazi, A. M., Nathwani, A. A., Ladhani, A., Qamar, F. N., Soofi, S. B., Memon, S. A., Soomro, J., Shaikh, S. A., Simms, V., Khan, P., & Ferrand, R. A. (2020). HIV infection predominantly affecting children in Sindh, Pakistan, 2019: A cross-sectional study of an outbreak. The Lancet Infectious Diseases, 20(3), 362-370. https://doi.org/10.1016/s1473-3099(19)30743-1
WHO. (2023). Management of HIV-infected children under 5 years of age with severe acute malnutrition. Www.who.int. https://www.who.int/tools/elena/interventions/hiv-sam
Manary, M., Trehan, I., & Willumsen, J. (2012). Systematic review of the care of HIV-infected children with severe acute malnutrition. https://www.who.int/docs/default-source/nutritionlibrary/publications/malnutrition/guideline-updates-on-the-management-of-severe-acute-malnutrition-in-infants-and-children/updates-management-sam-infantandchildren-review7.pdf
Temiye, E. O., Adeniyi, O. F., Fajolu, I. B., Ogbenna, A. A., Ladapo, T. A., Esezobor, C. I., Akinsulie, A. O., & Mabogunje, C. A. (2018). Human immunodeficiency virus status in malnourished children seen at Lagos. PLOS ONE, 13(10), e0200435. https://doi.org/10.1371/journal.pone.0200435
Van Gend, C. L., Haadsma, M. L., Sauer, P. J., & Schoeman, C. J. (2003). Evaluation of the WHO clinical case definition for pediatric HIV infection in Bloemfontein, South Africa. Journal of Tropical Pediatrics, 49(3), 143-147. https://doi.org/10.1093/tropej/49.3.143
Thurstans, S., Kerac, M., Maleta, K., Banda, T., & Nesbitt, A. (2008). HIV prevalence in severely malnourished children admitted to nutrition rehabilitation units in Malawi: Geographical & seasonal variations a cross-sectional study. BMC Pediatrics, 8(1). https://doi.org/10.1186/1471-2431-8-22
HIV/AIDS Data Hub for the Asia Pacific. (2023). HIV/AIDS Data Hub for the Asia Pacific. https://www.aidsdatahub.org/resource/pakistan-country-data-2023
Angami, K., Reddy, S. V. R., Singh, K. I., Singh, N. B., & Singh, P. I. (2004). Prevalence of HIV infection and AIDS symptomatology in malnourished children--a hospital based study. The Journal of Communicable Diseases, 36(1), 45–52. https://www.ncbi.nlm.nih.gov/pubmed/16295686
Asafo-Agyei, S. B., Antwi, S., & Nguah, S. B. (2013). HIV infection in severely malnourished children in Kumasi, Ghana: A cross-sectional prospective study. BMC Pediatrics, 13(1). https://doi.org/10.1186/1471-2431-13-181
UNAIDS. (2016). Ghana. Unaids.org. https://www.unaids.org/en/regionscountries/countries/ghana
Okechukwu, A. (2015). Burden of HIV infection in children with severe acute malnutrition at the University of Abuja teaching hospital Gwagwalada, Nigeria. Journal of HIV for Clinical and Scientific Research, 055-061. https://doi.org/10.17352/2455-3786.000015
UNAIDS. (2020). Country progress report -Nigeria Global AIDS Monitoring 2020. https://www.unaids.org/sites/default/files/country/documents/NGA_2020_countryreport.pdf
Intiful, F. D., Abdulai, H., Nyarko, R., Tette, E., & Asante, M. (2021). Malnutrition in HIV infected children on antiretroviral drugs in a cohort of Ghanaian children. Heliyon, 7(12), e08636. https://doi.org/10.1016/j.heliyon.2021.e08636
Nigussie, J., Girma, B., Molla, A., Mareg, M., & Mihretu, E. (2022). Under-nutrition and associated factors among children infected with human immunodeficiency virus in sub-Saharan Africa: A systematic review and meta-analysis. Archives of Public Health, 80(1). https://doi.org/10.1186/s13690-021-00785-z
Daka, D. W., & Ergiba, M. S. (2020). Prevalence of malnutrition and associated factors among adult patients on antiretroviral therapy follow-up care in Jimma Medical Center, Southwest Ethiopia. PLOS ONE, 15(3), e0229883. https://doi.org/10.1371/journal.pone.0229883
Simoni, J. M., Montgomery, A., Martin, E., New, M., Demas, P. A., & Rana, S. (2007). Adherence to antiretroviral therapy for pediatric HIV infection: A qualitative systematic review with recommendations for research and clinical management. Pediatrics, 119(6), e1371-e1383. https://doi.org/10.1542/peds.2006-1232
Fergusson, P., Tomkins, A., & Kerac, M. (2009). Improving survival of children with severe acute malnutrition in HIV-prevalent settings. International Health, 1(1), 10-16. https://doi.org/10.1016/j.inhe.2009.03.001
WHO. (2019). Consolidated guidelines on HIV testing services for a changing epidemic. Www.who.int. https://www.who.int/publications/i/item/WHO-CDS-HIV-19.31
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