Frequency of Relapse Rate after Treatment of Patients Addicted with Drugs Abuse (Opioids)
DOI:
https://doi.org/10.70749/ijbr.v3i2.622Keywords:
Opioid Addiction, Relapse Prevention, Holistic Treatment, Addiction Recovery, Multifactorial RisksAbstract
Objectives: frequency of relapse rate after treatment of patients addicted with drugs abuse (Opioids). Methodology: This descriptive study at CMH Lahore included 60 patients aged 18–60 years with a history of opioid addiction. Data on demographics, addiction history, and relapse, defined as re-use of opioids after detoxification and three months of treatment, were collected using a structured proforma. Patients were followed for three months post-treatment to record relapse occurrences and associated factors. Results: Of 60 patients revealed a relapse rate of 53.3% following opioid detoxification. Relapse was highest among males (56.1%), individuals with primary education (73.3%), and heroin users (58.8%). Age, socioeconomic status, living conditions, and duration of drug use showed no statistically significant associations with relapse. Prior detoxification also did not significantly impact relapse rates. Conclusion: Relapse in opioid addiction is multifactorial, necessitating holistic, individualized approaches to improve outcomes and reduce societal burden, considering demographic and clinical complexities for effective prevention and treatment strategies.
Downloads
References
Bradizza, C. M., Stasiewicz, P. R., & Paas, N. D. (2006). Relapse to alcohol and drug use among individuals diagnosed with co-occurring mental health and substance use disorders: A review. Clinical Psychology Review, 26(2), 162-178. https://doi.org/10.1016/j.cpr.2005.11.005
Hasin, D. S., O'Brien, C. P., Auriacombe, M., Borges, G., Bucholz, K., Budney, A., Compton, W. M., Crowley, T., Ling, W., Petry, N. M., Schuckit, M., & Grant, B. F. (2013). DSM-5 criteria for substance use disorders: Recommendations and rationale. American Journal of Psychiatry, 170(8), 834-851. https://doi.org/10.1176/appi.ajp.2013.12060782
Sapkota, S., Khadka, A., & Akela, G. (2017). Contributing factors to relapse of drug addiction among clients attending rehabilitation centres of Dharan, Nepal. Journal of Chitwan Medical College, 6(3), 20-25. https://doi.org/10.3126/jcmc.v6i3.16695
Sharma, A. K., Upadhyaya, S. K., Bansal, P., Nijhawan, M., & Sharma, D. K. (2012). A study of factors affecting relapse in substance abuse. Education, 2(17.033), 17-033. https://www.ijls.in/upload/1329773506PAPER_6.pdf
Degenhardt, L., Charlson, F., Ferrari, A., Santomauro, D., Erskine, H., Mantilla-Herrara, A., Whiteford, H., Leung, J., Naghavi, M., Griswold, M., Rehm, J., Hall, W., Sartorius, B., Scott, J., Vollset, S. E., Knudsen, A. K., Haro, J. M., Patton, G., Kopec, J., … Vos, T. (2018). The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990-2016: A systematic analysis for the global burden of disease study 2016. The Lancet Psychiatry, 5(12), 987-1012. https://doi.org/10.1016/s2215-0366(18)30337-7
Vanderplasschen, W., Colpaert, K., & Broekaert, E. (2010). Determinants of relapse and re-admission among alcohol abusers after intensive residential treatment. Archives of Public Health, 67(4). https://doi.org/10.1186/0778-7367-67-4-194
Rollins, A. L., O'Neill, S. J., Davis, K. E., & Devitt, T. S. (2005). Special Section on Relapse Prevention: Substance Abuse Relapse and Factors Associated With Relapse in an Inner-City Sample of Patients With Dual Diagnoses. Psychiatric Services, 56(10), 1274-1281. https://doi.org/10.1176/appi.ps.56.10.1274
Swanepoel, I., Geyer, S., & Crafford, G. (2016). Risk factors for relapse among young African adults following in-patient treatment for drug abuse in the Gauteng province. Social Work/Maatskaplike Werk, 52(3). https://doi.org/10.15270/52-3-517
Moradinazar, M., Farnia, V., Alikhani, M., Karyani, A. K., Rezaei, S., Rezaeian, S., Matin, B. K., & Najafi, F. (2020). Factors related to relapse in patients with substance-related disorders under methadone maintenance therapy: Decision tree analysis. Oman Medical Journal, 35(1), e89-e89. https://doi.org/10.5001/omj.2020.07
Sapkota, S., Khadka, A., & Akela, G. (2017). Contributing factors to relapse of drug addiction among clients attending rehabilitation centres of Dharan, Nepal. Journal of Chitwan Medical College, 6(3), 20-25. https://doi.org/10.3126/jcmc.v6i3.16695
San, L., Bernardo, M., Gómez, A., & Peña, M. (2012). Factors associated with relapse in patients with schizophrenia. International Journal of Psychiatry in Clinical Practice, 17(1), 2-9. https://doi.org/10.3109/13651501.2012.687452
Swanepoel, I., Geyer, S., & Crafford, G. (2016). Risk factors for relapse among young African adults following in-patient treatment for drug abuse in the Gauteng province. Social Work/Maatskaplike Werk, 52(3). https://doi.org/10.15270/52-3-517
Whiteford, H. A., Degenhardt, L., Rehm, J., Baxter, A. J., Ferrari, A. J., Erskine, H. E., Charlson, F. J., Norman, R. E., Flaxman, A. D., Johns, N., Burstein, R., Murray, C. J., & Vos, T. (2013). Global burden of disease attributable to mental and substance use disorders: Findings from the global burden of disease study 2010. The Lancet, 382(9904), 1575-1586. https://doi.org/10.1016/s0140-6736(13)61611-6
Swanepoel, I., Geyer, S., & Crafford, G. (2016). Risk factors for relapse among young African adults following in-patient treatment for drug abuse in the Gauteng province. Social Work/Maatskaplike Werk, 52(3). https://doi.org/10.15270/52-3-517
Andersson, H. W., Wenaas, M., & Nordfjærn, T. (2019). Relapse after inpatient substance use treatment: A prospective cohort study among users of illicit substances. Addictive Behaviors, 90, 222-228. https://doi.org/10.1016/j.addbeh.2018.11.008
Wesson, D. R., Havassy, B. E., & Smith, D. E. (1986). Theories of relapse and recovery and their implications for drug abuse treatment. NIDA Res Monogr, 72, 5-19. https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=363xYHsnProHNFVEAneS5M9PuxVVFeqra3c4ab60#page=14
Ms. Rizwana Rahool, National Drug Use Survey Pakistan 2022-24, Available from: https://www.unodc.org/pakistan/en/national-drug-use-survey-pakistan-2022-24--launched.html#:~:text=The%20overall%20results%20of%20the,tobacco%20in%20the%20preceding%20year
Rahman, M. M., Rahaman, M. M., Hamadani, J. D., Mustafa, K., & Shariful Islam, S. M. (2016). Psycho-social factors associated with relapse to drug addiction in Bangladesh. Journal of Substance Use, 21(6), 627-630. https://doi.org/10.3109/14659891.2015.1122099
Gul, B., Asghar, R., Ahmad, H. S., Shaheen, A., & Arshad, N. (2022). Relapse rate after opioid detoxification in drug addict patients. Journal of Rawalpindi Medical College, 26(2), 190-194. https://doi.org/10.37939/jrmc.v26i2.1751
Liu, N., Lu, Z., & Xie, Y. (2022). Tracking study on the relapse and aftercare effect of drug patients released from a compulsory isolated detoxification center. Frontiers in Psychiatry, 12. https://doi.org/10.3389/fpsyt.2021.699074
Maehira, Y., Chowdhury, E., Reza, M., Drahozal, R., Gayen, T., Masud, I., Afrin, S., Takamura, N., & Azim, T. (2013). Factors associated with relapse into drug use among male and female attendees of a three-month drug detoxification-rehabilitation programme in Dhaka, Bangladesh: A prospective cohort study. Harm Reduction Journal, 10(1), 14. https://doi.org/10.1186/1477-7517-10-14
Lara, G. L., Carlos, R., Constanza, D., Begoña, G., Diana, B., Laia, R. C., & Miquel, C. (2012). Risk factors for relapse in drug-dependent patients after hospital detoxification. Adicciones, 24(2). https://www.proquest.com/openview/7ca63e7e486d3ca86b031c2bf3c03305/1?pq-origsite=gscholar&cbl=2032270
Salimi, A., Safari, F., Mohajerani, S. A., Hashemian, M., Kolahi, A., & Mottaghi, K. (2014). Long-term relapse of ultra-rapid opioid detoxification. Journal of Addictive Diseases, 33(1), 33-40. https://doi.org/10.1080/10550887.2014.882727
Reus, V. I., Fochtmann, L. J., Bukstein, O., Eyler, A. E., Hilty, D. M., Horvitz-Lennon, M., Mahoney, J., Pasic, J., Weaver, M., Wills, C. D., McIntyre, J., Kidd, J., Yager, J., & Hong, S. (2018). The American psychiatric association practice guideline for the pharmacological treatment of patients with alcohol use disorder. American Journal of Psychiatry, 175(1), 86-90. https://doi.org/10.1176/appi.ajp.2017.1750101
Samir Bhandari, S. B., Maginsh Dahal, M. D., & Ganga Neupane, G. N. (2015). Factors associated with drug abuse relapse: a study on the clients of rehabilitation centers. Al Ameen J Med Sci, 8(4). 293-8. https://www.cabidigitallibrary.org/doi/full/10.5555/20153353737
Passetti, F., Clark, L., Davis, P., Mehta, M., White, S., Checinski, K., King, M., & Abou-Saleh, M. (2011). Risky decision-making predicts short-term outcome of community but not residential treatment for opiate addiction. Implications for case management. Drug and Alcohol Dependence, 118(1), 12-18. https://doi.org/10.1016/j.drugalcdep.2011.02.015
Salimi, A., Safari, F., Mohajerani, S. A., Hashemian, M., Kolahi, A., & Mottaghi, K. (2014). Long-term relapse of ultra-rapid opioid detoxification. Journal of Addictive Diseases, 33(1), 33-40. https://doi.org/10.1080/10550887.2014.882727
Smyth, B. P., Barry, J., Keenan, E., & Ducray, K. J. I. M. J. (2010). Lapse and relapse following inpatient treatment of opiate dependence. Ir Med J 103(6), 176-9. https://www.lenus.ie/handle/10147/110022
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Indus Journal of Bioscience Research

This work is licensed under a Creative Commons Attribution 4.0 International License.