Phytochemical and Pharmacological Analysis of Moringa Oleifera Leaves

Abstract

The use of medicinal plant extract-mediated treatment was found to be very effective in controlling bacterial infection. The plant moringa oleifera leaves was evaluated against gram negative pathogenic bacteria S. aureus, E. coli, S. typhi, P. aeruginosa. The methanolic extract of moringa oleifera leaves also possesses moderate antifungal activity against candida albicans and candida tropical The MeOH.Ext and Aq Ext of moringa oleiferawere screened for insecticidal activity, against three different insect species i.e. Tribolium castaneum, Rhyzopertha dominica and Callosobruchus analis, revealed that MeOH.Ext and Aq Ext of the plant, showed significant activity against the tested insects.. The methanolic extract showed significant result in growth inhibition at concentrations of 1000 and 100  µg/ml, respectively. While no phytotoxic activity was observed at concentration 10 µg/ml. The MeOH Ext and Aq Ext ofmoringa oleifera show no hemagglutination activity against human red blood cell. The search for plant-based antimicrobials is growing due to rising resistance, high costs, and reduced efficacy of conventional medicines. Moringa oleifera has shown potential as a natural antimicrobial agent, though its active compounds were not fully assessed. This study identified inhibitory plant compounds against tested pathogens, suggesting their promising role in pharmaceutical applications. These findings highlight M. oleifera as a potential source of novel antimicrobials for controlling pathogenic bacteria effectively.