Effectiveness of Microvascular Decompression (MVD) for Trigeminal Neuralgia (TGN) in Terms of Improvement in Facial Pain
DOI:
https://doi.org/10.70749/ijbr.v3i3.2269Keywords:
Trigeminal, pain, neuralgia, decompressionAbstract
Background: For intractable TN of any kind and other cranial nerve issues, micro-vascular decompression (MVD) is currently the gold standard surgical technique. With few complications and little post-operative pain, it is the preferred safe and efficient treatment for persistent pain for people of all ages. The purpose of this study was to assess how well microvascular decompression (MVD) worked to treat idiopathic trigeminal neuralgia in terms of post-operative pain alleviation. Place and Duration: Conducted at the department of Neurosurgery, Mardan Medical Complex, Mardan, for the duration from May 2024 to December 2024. Methodology: 67 patients between the ages of 40 and 70 who had unilateral idiopathic trigeminal neuralgia lasting longer than three months were included. Patients with bilateral trigeminal neuralgia, h/o micro-vascular decompression, and a history of rhizotomy or sclerosing agent injections in the trigeminal nerve route were not included. Every patient had the microvascular decompression operation. Every patient was monitored after surgery, and on the seventh post-operative day, the final result (in terms of post-operative pain) was recorded as satisfactory or unsatisfactory. Results: It was 56.57 ± 8.19 years old on average. With a female to male ratio of 1.6:1, 41 (61.19%) of the 67 patients were female and 26 (38.81%) were male. The average pain scores before and after surgery were 7.09 ± 1.60 and 1.40 ± 2.68, respectively. 51 patients (76.12%) had satisfactory results, while 16 individuals (23.88%) had bad results. Conclusion: This study finds that while treating idiopathic trigeminal neuralgia, microvascular decompression (MVD) has a high frequency of favorable results (in terms of post-operative pain alleviation).
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1. Maarbjerg S, Di Stefano G, Bendtsen L, Cruccu G. Trigeminal neuralgia — diagnosis and treatment. Cephalalgia. 2017;37:648—57. http://dx.doi.org/10.1177/0333102416687280.
2. Bendtsen L, Zakrzewska JM, Abbott J, Braschinsky M, Di Stefano G, Donnet A, et al. European Academy of Neurology guide line on trigeminal neuralgia. Eur J Neurol. 2019;26:831—49.
http://dx.doi.org/10.1111/ene.13950.
3. Ruiz-Juretschke F, González-Quarante LH, García-Leal R, Martínez de Vega V. Neurovascular relations of the trigeminal nerve in asymptomatic individuals studied with high-resolution three-dimensional magnetic resonance imaging. Anat Rec. 2019;302:639—45.
http://dx.doi.org/10.1002/ar.23818.
4. Gambeta E, Chichorro JG, Zamponi WG. Trigemi nal neuralgia: an overview from pathophysiology to pharmacological treatments. Mol Pain. 2020;16:1—39.
http://dx.doi.org/10.1177/1744806920901890.
5. Fernández Rodríguez B, Simonet C, Cerdán DM, Morol lón N, Guerrero P, Tabernero C, et al. Familial classic trigeminal neuralgia. Neurol (Engl Ed). 2019;34:229—33, http://dx.doi.org/10.1016/j.nrleng.2016.12.003.
6. Jafree DJ, Zakrzewska JM. Long-term pain relief at five years after medical, repeat surgical procedures or no management for recurrence of trigeminal neu ralgia after microvascular decompression: analysis of a historical cohort. Br J Neurosurg. 2019;33:31—6.
http://dx.doi.org/10.1080/02688697.2018.1538484.
7. Cheng J, Meng J, Lei D, Hui X. Repeat microvas cular decompression for patients with persistent or recurrent trigeminal neuralgia: prognostic factors and long-term outcomes. Medicine (United States). 2019;98.
http://dx.doi.org/10.1097/MD.0000000000015167.
8. Xu R, Xie ME, Jackson CM. Trigeminal neuralgia: current approaches and emerging interventions. J Pain Res. 2021;14:3437-63.
http://dx.doi.org/10.2147/JPR.S331036.
9. Danyluk H, Lang S, Monchi O, Sankar T. Pre-operative limbic system functional connectivity distinguishes responders from non-responders to surgical treatment for trigeminal neuralgia. Front Neurol. 2021;12:716500.
http://dx.doi.org/10.3389/fneur.2021.716500.
10. Sandell T, Eide PK. Effect of microvascular decompression in trigeminal neuralgia patients with or without constant pain. J Operat Neurosurg. 2008;63:93-100.
https://doi.org/10.1227/01.neu.0000316856.32104.65
11. Louges MA, Kleiber JC, Bazin A, Chays A, Dubernard X. Efficacy of microsurgical vascular decompression in trigeminal neuralgia. Eur Ann Otorhinolaryngol Head Neck Dis. 2020;137:285-9.
http://dx.doi.org/10.1016/j.anorl.2019.09.008.
12. Ayele BA, Mengesha AT, Zewde YZ. Clinical characteristics and associated factors of trigeminal neuralgia: experience from Addis Ababa, Ethiopia. BMC Oral Health. 2020;20:244.
http://dx.doi.org/10.1186/s12903-020-01227-y.
13. De Stefano G, Litewczuk D, Mollica C. Sex differences in trigeminal neuralgia: a focus on radiological and clinical characteristics. Neurol Sci. 2023;44:4465-72.
http://dx.doi.org/10.1007/s10072-023-06923-5.
14. Wei Y, Pu C, Li N, Cai Y, Shang H, Zhao W. Long term therapeutic effect of microvascular decompression for trigeminal neuralgia: Kaplan—Meier analysis in a consecu tive series of 425 patients. Turk Neurosurg. 2018;28:88—93,
http://dx.doi.org/10.5137/1019-5149.JTN.18322-16.1.
15. Holste K, Chan AY, Rolston JD, Englot DJ. Pain out comes following microvascular decompression for drug-resistant trigeminal neuralgia: a systematic review and meta-analysis. Clin Neurosurg. 2020;86:182—90,
http://dx.doi.org/10.1093/neuros/nyz075.
16. Paulo DL, Lopez AM, Jermakowicz WJ, Yu H, Shah H, Konrad PE, Englot DJ. Microvascular decompression for trigeminal neuralgia in patients with multiple sclerosis: predictors of treatment success. World Neurosurg. 2020;136:e165-70.
http://dx.doi.org/10.1016/j.wneu.2019.12.081.
17. Zhao Y, Zhang X, Yao J, Li H, Jiang Y. Microvascular decompression for trigeminal neuralgia due to venous compression alone. J Craniofac Surg. 2018;29:178-81.
http://dx.doi.org/10.1097/SCS.0000000000004174.
18. Arkawazi BM, Faraj MK. Treatment of primary trigeminal neuralgia: a comparative study of microvascular decompression surgery and stereotactic gamma knife radiosurgery. NeuroQuantology. 2022;20:3738-50.
19. Andersen AS, Heinskou TB, Rochat P. Microvascular decompression in trigeminal neuralgia - a prospective study of 115 patients. J Headache Pain. 2022;23:145.
http://dx.doi.org/10.1186/s10194-022-01520-x.
20. Hitchon PW, Bathla G, Moritani T, Holland MT, Noeller J, Nourski KV. Predictability of vascular conflict by MRI in trigeminal neuralgia. Clin Neurol Neurosurg. 2019;182:171—6. http://dx.doi.org/10.1016/j.clineuro.2019.05.005.
21. Sulaiman I, Abduljabbar Omar A, Hussein Hameed S. The Impact of Microvascular Decompression on Pain Management in Trigeminal Neuralgia: Clinical Insights. Cureus 2024;16(12): e75987.
http://dx.doi.org/10.7759/cureus.75987.
22. Pascasioa LA, Casa-Fagesa BD, de Antonioa EE, Grandasa F, García-Leal R, Juretschke FR. Microvascular decompression for trigeminal neuralgia: A retrospective analysis of long-term outcomes and prognostic factors. Neurología. 2023;38:625—634.
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