Outcome of Single Tract Percutaneous Nephrolithotomy in Patients Presenting with Staghorn Calculus at Tertiary Care Hospital, Islamabad

Authors

  • Hamad Ali Shah Department of Urology and Surgery, KRL Hospital, Islamabad, Pakistan. https://orcid.org/0009-0000-3161-6623
  • Asaf Alam Khan Department of Urology and Surgery, KRL Hospital, Islamabad, Pakistan.
  • Zeeshan Ahmed Department of Urology and Surgery, KRL Hospital, Islamabad, Pakistan.
  • Muhammad Arsalan Ali Department of Urology and Surgery, KRL Hospital, Islamabad, Pakistan.
  • Shahzeb Habib Department of Urology and Surgery, KRL Hospital, Islamabad, Pakistan.
  • Muhammad Tahir Usman Department of Surgery, Sir Ganga Ram Hospital, Lahore, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i3.2349

Keywords:

Transfusion, Percutaneous nephrolithotomy, staghorn calculi, stone-free rate, complications, Islamabad.

Abstract

Background: Percutaneous nephrolithotomy (PCNL) is one of the most effective and less invasive surgeries for treating renal calculi, especially staghorn calculi. Several factors determine early success rates of PCNL, including stone size, composition, and location, specific to the patient, comorbid conditions, and body habitus. Objectives: The purpose of this study was to determine the efficacy of single tract percutaneous nephrolithotomy (PCNL) specifically assessing complications, transfusion requirement and stone free rate in staghorn renal calculi in a tertiary care hospital in Islamabad. Methods: This study was a prospective descriptive cross-sectional study which was carried for six months in the KRL Hospital in Islamabad after approval from ERB (KRL-HI-PUB-ERC/Dec23/01). Among the 194 patients, 100 were male and 94 were female. Thus, information regarding the patients’ characteristics and the operation features as well as the profiles and details of the complications during the peri-operative period were documented. Stone clearance below medical management was considered as fragments of ≤ 0.4 cm. Results: A stone-free rate of 66.5% was established and females' treatment was more effective, showing 78.7%, while males had only 55%. Regarding transfusions, 27·8% of patients required a transfusion. Both obesity and longer operation duration affected the stone clearance rates with a mixed trend. Side effects, including short-term fever and urinary incontinence, were rare and could easily be controlled. Conclusion: Single-tract PCNL is highly effective and safe in managing staghorn calculi and should continue to be advocated in developing countries with limited resources. Still, clearance rates are impressive, and complications are low.

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References

1. Ali M, Naeem Q, Zafar U, Abbas A, Muhammad F, Naqash M, et al. Outcomes and complications of percutaneous nephrolithotomy (PCNL): a single-center experience. Cureus. 2024;16(9):e69567.

https://doi.org/10.7759/cureus.69567

2. Memon I, Soomro N, Hussain SA, Shah SAR, Rajpar ZH, Sheikh A. Percutaneous nephrolithotomy versus open surgery in patients presenting with renal staghorn stones: a single-center study. Rawal Med J. 2022;47(2):388.

3. Iqbal N, Iqbal S, Hasan A, Majeed M, Iqbal D, Shahzad M, et al. Outcomes of percutaneous nephrolithotomy in elder age patients: single center experience. J Ayub Med Coll Abbottabad. 2021;33(2):217–21.

4. Iqbal N, Hasan A, Malik HA, Khan R, Nazar A, Khawaja MA. A comparison of complications and success rates after PCNL in younger and elderly patients. J Coll Physicians Surg Pak. 2020;30(12):1316–20.

https://doi.org/10.29271/jcpsp.2020.12.1316

5. Ahmad A, Mishra KG, Gunjan K. Tubeless PCNL in macrotract for multiple and staghorn calculus with more than one tract: a single centre experience and literature review. J Evol Med Dent Sci. 2020;9(15):1295–300.

https://doi.org/10.14260/jemds/2020/281

6. Tsai IC, Chen ZH, Lee KH, Liu CL, Huang SK, Chiu AW. Single versus multiple mini-tract percutaneous nephrolithotomy for staghorn renal stone: a single-center study. Urol Sci. 2022;33(1):35–41.

https://doi.org/10.4103/uros.uros_138_20

7. Deole S, Ghagane SC, Patel P, Nerli RB, Patil SD, Dixit NS. Outcome of percutaneous nephrolithotomy in a tertiary care center in North Karnataka. World J Nephrol Urol. 2020;9(2):35–9.

8. Aher N, Sekar H, Kumaresan N, Krishnamoorthy S. Revisiting standard percutaneous nephrolithotomy in the mini-percutaneous nephrolithotomy/retrograde intrarenal surgery era: a retrospective audit. Cureus. 2024;16(10):e71847.

https://doi.org/10.7759/cureus.71847

9. Thorat GN, Deshmukh MP, Avhad ADM, Rairikar SV, Ambekar AP. Assessment of clinical profile and outcome of different surgical treatment modalities among patients with renal calculi in tertiary care hospitals in Mumbai. NeuroQuantology. 2022;20(16):910.

10. Pipal DK, Jain S, Biswas P. A huge staghorn renal stone: is there still a need for open surgery to protect against further damage to the kidney? A case report. Qatar Med J. 2023;2023(4):30.

https://doi.org/10.5339/qmj.2023.30

11. Amin MM, El-Feky MM, Abozied HAM, Farid MM. Predictive factors of the outcomes of percutaneous nephrolithotomy for staghorn renal stones. Al-Azhar Int Med J. 2022;3(6):8–13.

https://doi.org/10.21608/aimj.2022.107043.1671

12. Fareed R, Agarwal BK. Tubeless percutaneous nephrolithotomy (PCNL) as standard treatment: observations from a tertiary care hospital. Int J Surg. 2021;5(1):277–80.

https://doi.org/10.33545/surgery.2021.v5.i1e.623

13. Khadgi S, El-Nahas AR, El-Shazly M, Al-Terki A. Comparison of standard and mini-percutaneous nephrolithotomy for staghorn stones. Arab J Urol. 2021;19(2):147–51.

https://doi.org/10.1080/2090598x.2021.1878670

14. Akhtar M, Ullah MS, Lodhi MHK, Aslam N, Zafar Z, Raza QH, et al. Stone clearance rate in patients treated with percutaneous nephrolithotomy versus open surgery for the management of staghorn renal calculi. Pak J Med Health Sci. 2022;16(9):731.

https://doi.org/10.53350/pjmhs22169731

15. Kang DE, Maloney MM, Haleblian GE, Springhart WP, Honeycutt EF, Eisenstein EL, et al. Effect of medical management on recurrent stone formation following percutaneous nephrolithotomy. J Urol. 2007;177:1785–8.

https://doi.org/10.1016/j.juro.2007.01.061

16. Lee MJ, Kim JK, Tang J, Ming JM, Chua ME. The efficacy and safety of tranexamic acid in the management of perioperative bleeding after percutaneous nephrolithotomy: a systematic review and meta-analysis of comparative studies. J Endourol. 2022;36(3):303–12.

https://doi.org/10.1089/end.2021.0498

17. Batagello CA, Vicentini FC, Monga M, Miller AW, Marchini GS, Torricelli FCM, et al. Tranexamic acid in patients with complex stones undergoing percutaneous nephrolithotomy: a randomised, double-blinded, placebo-controlled trial. BJU Int. 2022;129(1):35–47.

https://doi.org/10.1111/bju.15378

18. Kukreja R, Desai M, Patel S, et al. Factors affecting blood loss during percutaneous nephrolithotomy: prospective study. J Endourol. 2004;18(8):715–22.

https://doi.org/10.1089/0892779042360599

19. Ijaz T, Wazir BG, Shamsher MA. Comparison of outcomes of single versus multiple mini-tract percutaneous nephrolithotomy for staghorn renal stone clearance. Pak J Med Health Sci. 2022;16(12):664.

https://doi.org/10.53350/pjmhs20221612664

20. Ali S, Kumar N, Baloch U. Outcome of percutaneous nephrolithotomy. J Coll Physicians Surg Pak. 2014;24(4):261–4.

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Published

2025-03-31

How to Cite

Shah, H. A., Khan, A. A., Ahmed, Z., Ali, M. A., Habib, S., & Usman, M. T. (2025). Outcome of Single Tract Percutaneous Nephrolithotomy in Patients Presenting with Staghorn Calculus at Tertiary Care Hospital, Islamabad. Indus Journal of Bioscience Research, 3(3), 801-804. https://doi.org/10.70749/ijbr.v3i3.2349