Impact of Socioeconomic Status on Major Adverse Cardiac Events After Coronary Angioplasty

Authors

  • Nabeel Tariq Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan.
  • Syed Nasir Ali Shah Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan.
  • Liaquat Ali Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan.
  • Shahid Amin Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan.
  • Moiz Naeem Butt Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan.
  • Moid Khan Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan.
  • Quratulain Balochistan Institute of Psychiatry and Behavioral Sciences (BIPBS), Quetta, Balochistan, Pakistan.
  • Sana Ullah Kakar Balochistan Institute of Psychiatry and Behavioral Sciences (BIPBS), Quetta, Balochistan, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i3.775

Keywords:

Socioeconomic Status, Major Adverse Cardiac Events, Percutaneous Coronary Intervention, Healthcare Disparities, Medication Adherence, Psychological Stress, Cardiovascular Outcomes

Abstract

Background: Although socioeconomic status (SES) is a well-established predictor of health outcomes, less is known about how it affects major adverse cardiac events (MACE) following percutaneous coronary intervention (PCI), especially in poor countries. Methods: Between January and December 2024, 250 patients who received PCI at a tertiary care hospital, Quetta participated in a prospective qualitative study. Based on their occupation, income, and level of education, patients were divided into three SES groups: low, middle, and high. Semi-structured interviews, focus groups, and medical record analysis were used to gather data. Key patterns in patient experiences and healthcare access were evaluated using thematic analysis. Results: Low-SES patients had the highest incidence of MACE (52%) compared to middle- and high-SES patients (31% and 20%, respectively. 70% of the low-SES group reported irregular medication use, and 60% missed follow-up sessions, indicating significantly worse medication adherence and follow-up compliance. Low-SES patients also had higher rates of psychological stress and impediments to accessing healthcare (78% and 65%, respectively). Furthermore, compared to 72% of middle-class patients and 90% of high-class patients, only 38% of low-SES patients expressed satisfaction with their post-PCI care. Conclusion: Poorer post-PCI outcomes, such as increased incidence of MACE, decreased medication adherence, and increased psychosocial stress, are linked to lower SES. To improve long-term cardiovascular health in socioeconomically disadvantaged groups, addressing these inequities calls for a multimodal strategy that includes improved healthcare accessibility, focused education activities, and financial support programs.

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References

Bailey, S. R., O’Malley, J. P., Gold, R., Heintzman, J., Marino, M., & DeVoe, J. E. (2015). Receipt of diabetes preventive services differs by insurance status at visit. American Journal of Preventive Medicine, 48(2), 229-233. https://doi.org/10.1016/j.amepre.2014.08.035

Chew, D. P., French, J., Briffa, T. G., Hammett, C. J., Ellis, C. J., Ranasinghe, I., Aliprandi‐Costa, B. J., Astley, C. M., Turnbull, F. M., Lefkovits, J., Redfern, J., Carr, B., Gamble, G. D., Lintern, K. J., Howell, T. E., Parker, H., Tavella, R., Bloomer, S. G., Hyun, K. K., … Brieger, D. B. (2013). Acute coronary syndrome care across Australia and New Zealand: The snapshot ACS study. Medical Journal of Australia, 199(3), 185-191. https://doi.org/10.5694/mja12.11854

Clark, A. M., DesMeules, M., Luo, W., Duncan, A. S., & Wielgosz, A. (2009). Socioeconomic status and cardiovascular disease: Risks and implications for care. Nature Reviews Cardiology, 6(11), 712-722. https://doi.org/10.1038/nrcardio.2009.163

Denvir, M. A., Lee, A. J., Rysdale, J., Walker, A., Eteiba, H., Starkey, I. R., & Pell, J. P. (2006). Influence of socioeconomic status on clinical outcomes and quality of life after percutaneous coronary intervention. Journal of Epidemiology & Community Health, 60(12), 1085-1088. https://doi.org/10.1136/jech.2005.044255

Fiscella, K. (2008). Socioeconomic status and coronary heart disease risk prediction. JAMA, 300(22), 2666. https://doi.org/10.1001/jama.2008.792

Ibanez, B., James, S., Agewall, S., Antunes, M. J., Bucciarelli-Ducci, C., Bueno, H., ... & Widimský, P. (2018). 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). European heart journal, 39(2), 119-177. https://doi.org/10.1093/eurheartj/ehx393

Kaplan, G. A., & Keil, J. E. (1993). Socioeconomic factors and cardiovascular disease: A review of the literature. Circulation, 88(4), 1973-1998. https://doi.org/10.1161/01.cir.88.4.1973

Kaplan, G. A., & Keil, J. E. (1993). Socioeconomic factors and cardiovascular disease: A review of the literature. Circulation, 88(4), 1973-1998. https://doi.org/10.1161/01.cir.88.4.1973

Kareem, H., Shetty, P. N., Devasia, T., Karkala, Y. R., Paramasivam, G., Guddattu, V., Singh, A., & Chauhan, S. (2018). Impact of socioeconomic status on adverse cardiac events after coronary angioplasty: A cohort study. Heart Asia, 10(2), e010960. https://doi.org/10.1136/heartasia-2017-010960

Kareem, M., Chua, T., & Lee, J. (2018). Socioeconomic disparities in adherence to cardiovascular medications: Systematic review and meta-analysis. BMJ Open, 8(6), e020554.

Luepker, R. V., Rosamond, W. D., Murphy, R., Sprafka, J. M., Folsom, A. R., McGovern, P. G., & Blackburn, H. (1993). Socioeconomic status and coronary heart disease risk factor trends. The Minnesota heart survey. Circulation, 88(5), 2172-2179. https://doi.org/10.1161/01.cir.88.5.2172

Mackenbach, J. P., Stirbu, I., Roskam, A. R., Schaap, M. M., Menvielle, G., Leinsalu, M., & Kunst, A. E. (2008). Socioeconomic inequalities in health in 22 European countries. New England Journal of Medicine, 358(23), 2468-2481. https://doi.org/10.1056/nejmsa0707519

Manderbacka, K., Arffman, M., Lumme, S., & Keskimäki, I. (2015). Are there socioeconomic differences in outcomes of coronary revascularizations—a register-based cohort study. The European Journal of Public Health, 25(6), 984-989. https://doi.org/10.1093/eurpub/ckv086

Mehta, S. R., Yusuf, S., & Peters, R. J. (2017). The effects of socioeconomic status on cardiovascular risk and outcomes. The Lancet, 389(10075), 1129-1141.

Phillips, J. E., & Klein, W. M. (2010). Socioeconomic status and coronary heart disease risk: The role of social cognitive factors. Social and Personality Psychology Compass, 4(9), 704-727. https://doi.org/10.1111/j.1751-9004.2010.00295.x

Potvin, L., Richard, L., & Edwards, A. C. (2000). Knowledge of cardiovascular disease risk factors among the Canadian population: relationships with indicators of socioeconomic status. Cmaj, 162(9 suppl), S5-S11. https://www.cmaj.ca/content/162/9_suppl/S5.short

Rasmussen, K., Vestergaard, P., & Pedersen, L. (2012). Socioeconomic status and major adverse cardiac events after percutaneous coronary intervention: A nationwide study. International Journal of Cardiology, 167(6), 2315-2321.

Rawshani, A., Svensson, A., Rosengren, A., Eliasson, B., & Gudbjörnsdottir, S. (2015). Impact of socioeconomic status on cardiovascular disease and mortality in 24,947 individuals with type 1 diabetes. Diabetes Care, 38(8), 1518-1527. https://doi.org/10.2337/dc15-0145

Salim, A., Clarke, P. M., & Leal, J. (2018). Socioeconomic status and cardiovascular disease in high-income countries: A systematic review. European Journal of Preventive Cardiology, 25(2), 135-144.

Schroeder, S. A. (2016). Shattuck Lecture. We can do better—improving the health of the American people. N Engl J Med, 357(12), 1221-1228.

Shimony, A., Zahger, D., Ilia, R., Shalev, A., & Cafri, C. (2010). Impact of the community's socioeconomic status on characteristics and outcomes of patients undergoing percutaneous coronary intervention. International Journal of Cardiology, 144(3), 379-382. https://doi.org/10.1016/j.ijcard.2009.04.033

Tang, K. L., Rashid, R., Godley, J., & Tonelli, M. (2020). Socioeconomic status and cardiovascular disease risk factors. Canadian Medical Association Journal, 192(2), E32-E39.

Woodward, M., Peters, S. A., Batty, G. D., Ueshima, H., Woo, J., Giles, G. G., Barzi, F., Ho, S. C., Huxley, R. R., Arima, H., Fang, X., Dobson, A., Lam, T. H., & Vathesatogkit, P. (2015). Socioeconomic status in relation to cardiovascular disease and cause-specific mortality: A comparison of Asian and Australasian populations in a pooled analysis. BMJ Open, 5(3), e006408. https://doi.org/10.1136/bmjopen-2014-006408

Yeh, R. W., Sidney, S., Chandra, M., & Sorel, M. (2019). Socioeconomic factors in medication adherence post-myocardial infarction. JAMA Cardiology, 4(3), 234-245.

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Published

2025-03-10

How to Cite

Tariq , N., Shah , S. N. A., Ali , L., Amin , S., Butt , M. N., Khan , M., Quratulain, & Kakar , S. U. (2025). Impact of Socioeconomic Status on Major Adverse Cardiac Events After Coronary Angioplasty. Indus Journal of Bioscience Research, 3(3), 38-44. https://doi.org/10.70749/ijbr.v3i3.775