Exploring the Role of Psychobiotics in Mental and Emotional Well-being and How Psychobiotics Can Help Fight Anxiety and Depression
DOI:
https://doi.org/10.70749/ijbr.v3i3.823Keywords:
Gut Microbiota, Micro Biota-gut-Brain Axis, Probiotics, Psychobiotics, CNS, Depression, Neurotransmitter, Neuron Connections, Serotonin, DopamineAbstract
Human health relies heavily on gut microbiota because this microbe system affects both brain function and behavior while influencing the stress response mechanism through the microbiota-gut-brain axis. Probiotics and their specific type psychobiotics develop as innovative treatments which help individuals manage mental health conditions along with CNS diseases and treat depression and anxiety symptoms. A sufficient consumption of psychobiotics as live organisms offers mental health benefits by allowing them to engage with gut microbiota for controlling neurotransmitter synthesis and immune responses together with inflammation regulation. The current studies demonstrate how probiotics and prebiotics generate beneficial results which enhance mind performance and stress reduction and improve mood. This review reviews the influence of psychobiotics on neuron connections between the gut and brain through studies about how they affect serotonin and dopamine neural pathways and immune responses and their health benefits within fermented foods. The gut microbiota plays a crucial role in overall health by influencing brain function, mood, and stress responses through the microbiota-gut-brain axis. Probiotics and prebiotics help maintain a balanced gut microbiome, supporting mental performance, emotional stability, and immune function. Research links gut dysbiosis to various health disorders, highlighting probiotic foods like yogurt and kefir as potential treatments for anxiety, depression, and irritable bowel syndrome. Beneficial microorganisms such as Lactobacillus, Bifidobacterium, and Saccharomyces boulardii improve gut health. Advancing psychobiotics research will enhance mental healthcare strategies, offering innovative solutions for global health challenges and overall well-being.
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References
Appanna, V. D. (2018). Human microbes - the power within: Health, Healing and Beyond. Springer.
Avanzini, G. (1992). Neurotransmitters in epilepsy: Epilepsy Research Supplements, Volume 8. Elsevier.
Baldo, L., Riera, J. L., Tooming-Klunderud, A., Albà, M. M., & Salzburger, W. (2015). Gut Microbiota Dynamics during Dietary Shift in Eastern African Cichlid Fishes. PLoS ONE, 10(5), e0127462. https://doi.org/10.1371/journal.pone.0127462
Chandan, R. C., White, C. H., Kilara, A., & Hui, Y. H. (2008). Manufacturing yogurt and fermented milks. John Wiley & Sons.
Charalampopoulos, D., & Rastall, R. A. (2009a). Prebiotics and probiotics science and technology. Springer Science & Business Media.
Charalampopoulos, D., & Rastall, R. A. (2009b). Prebiotics and probiotics science and technology. Springer Science & Business Media.
Chen, W., & Narbad, A. (2018). Lactic acid bacteria in foodborne Hazards reduction: Physiology to Practice. Springer.
Cowan, C., & Leonard, B. (2021a). Microbes and the mind: The Impact of the Microbiome on Mental Health. Karger Medical and Scientific Publishers.
Cowan, C., & Leonard, B. (2021b). Microbes and the mind: The Impact of the Microbiome on Mental Health. Karger Medical and Scientific Publishers.
Cummings, J. H., Rombeau, J. L., & Sakata, T. (2004). Physiological and clinical aspects of Short-Chain fatty acids. Cambridge University Press.
Gibson, G., & Roberfroid, M. (2013b). Colonic microbiota, nutrition and health. Springer Science & Business Media.De W Blackburn, C. (2006). Food spoilage microorganisms. Woodhead Publishing.
Elmer, G. W., Mcfarland, L. V., Mcfarland, M., & Russo, E. B. (2013). The power of probiotics: Improving Your Health with Beneficial Microbes. Routledge.
Evrensel, A., & Ünsalver, B. Ö. (2018). Gut microbiota: Brain Axis. BoD – Books on Demand.
Gibson, G., & Roberfroid, M. (2013). Colonic microbiota, nutrition and health. Springer Science & Business Media.
Cryan, J. F., & Clarke, G. (2016). Gut microbiome and behavior (Vol. 131). Academic Press.
Abbo, S., Gopher, A., & Bar-Gal, G. K. (2022). Plant domestication and the origins of agriculture in the ancient Near East. Cambridge University Press.
He, W. (2024). Insights in Microorganisms in Vertebrate Digestive Systems: 2022. Frontiers Media SA.
Herbel, S., & Gaines, D. (2010). Women’s issues in transportation: Summary of the 4th International Conference. Conference overview and plenary papers. Transportation Research Board.
Hyland, N., & Stanton, C. (2023). The Gut-Brain axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota. Elsevier.
Lee, B. H. (2021). Neuroprotection: Rescue from Neuronal Death in the Brain. Mdpi AG.
Furness, J. B., & Costa, M. (1987). The enteric nervous system.
Lyte, M., & Freestone, P. P. (2010a). Microbial endocrinology: Interkingdom Signaling in Infectious Disease and Health. Springer Science & Business Media.
Lyte, M., & Freestone, P. P. (2010b). Microbial endocrinology: Interkingdom Signaling in Infectious Disease and Health. Springer Science & Business Media.
Lyte, M., & Freestone, P. P. (2010c). Microbial endocrinology: Interkingdom Signaling in Infectious Disease and Health. Springer Science & Business Media.
Martin, C. R., & Larkin, D. (2018). Probiotics in mental health. CRC Press.
Mba, E. a. R. M. P., & Hobbins, J. C. (2008). Handbook of Clinical Obstetrics: The Fetus and Mother. John Wiley & Sons.
Medicine, I. O., Board, F. a. N., & Forum, F. (2013a). The human microbiome, diet, and health: Workshop Summary. National Academies Press.
Medicine, I. O., Board, F. a. N., & Forum, F. (2013b). The human microbiome, diet, and health: Workshop Summary. National Academies Press.
Microbiology of waterborne diseases: Microbiological Aspects and Risks. (2013). Academic Press.
Mueser, K. T., & Jeste, D. V. (2011). Clinical Handbook of Schizophrenia. Guilford Press.
Organization, W. H. (2012). Dementia: A Public Health Priority.
Osborne, N. N., & Hamon, M. (1988). Neuronal serotonin.
Pasterkamp, J., Smidt, M. P., & Burbach, J. P. H. (2009). Development and engineering of dopamine neurons. Springer Science & Business Media.
Pittman, R. N. (2016). Regulation of Tissue Oxygenation, second edition. Biota Publishing.
Rao, V., & Rao, L. (2016). Probiotics and prebiotics in human nutrition and health. BoD – Books on Demand.
Schwenk, D. (2011). Cultured food life: Learn to Make Probiotic Foods in Your Home. Xlibris Corporation.
Serotonin - neurotransmitter and hormone of brain, bowels and blood. (2023). In IntechOpen eBooks. https://doi.org/10.5772/intechopen.1000435
Singh, A. K., & Williams, G. H. (2009). Textbook of Nephro-Endocrinology. Academic Press.
Singh, B. (2018). NanoNutraceuticals. CRC Press.
Singh, R. L., & Mondal, S. (2019a). Food safety and human health. Academic Press.
Singh, R. L., & Mondal, S. (2019b). Food safety and human health. Academic Press.
Singh, R. P., Kothari, R., Koringa, P. G., & Singh, S. P. (2017). Understanding Host-Microbiome Interactions - an Omics approach: Omics of Host-Microbiome Association. Springer.
Tache, Y., & Wingate, D. L. (1991). Brain-Gut interactions. CRC Press.
The Hypothalamus-Pituitary-Adrenal Axis. (2008). Elsevier.
Venema, K., & Carmo, A. P. D. (2015). Probiotics and prebiotics: Current Research and Future Trends. Caister Academic Press Limited.
Watson, R. R., & Preedy, V. R. (2015a). Probiotics, prebiotics, and synbiotics: Bioactive Foods in Health Promotion. Academic Press.
Watson, R. R., & Preedy, V. R. (2015b). Probiotics, prebiotics, and synbiotics: Bioactive Foods in Health Promotion. Academic Press.
Yildiz, F. (2016). Development and manufacture of yogurt and other functional dairy products. CRC Press.
Zhu, C., Xu, S., Jiang, R., Yu, Y., Bian, J., & Zou, Z. (2024). The gasdermin family: emerging therapeutic targets in diseases. Signal Transduction and Targeted Therapy, 9(1). https://doi.org/10.1038/s41392-024-01801-8
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