Effect of Diode Laser Cycloablation in the Treatment of Refractory Glaucoma
DOI:
https://doi.org/10.70749/ijbr.v3i3.891Keywords:
Refractory Glaucoma, Diode Laser, Intraocular PressureAbstract
Background: In developing countries, limited resources and ophthalmologists hinder glaucoma care. Diode Laser Trans-scleral Cycloablation (DLCA) offers a simple, cost-effective treatment for refractory glaucoma. This study aims to address the insufficient literature on DLCA outcomes. Objectives: To determine the frequency of success of DLCA in reducing intraocular pressure (IOP) in refractory glaucoma. Study Design: Descriptive case series. Settings and Duration: Department of Ophthalmology, LRBT Eye Hospital, Lahore, from 8th May to 7th November 2024. Methodology: Seventy-three patients aged 18–65 years with refractory glaucoma were included. Patients with thin sclera, scleral atrophy, or prior trans-scleral cyclophotocoagulation were excluded. DLCA was performed using an 810 nm laser, with a power of 1500–2000 mW and a 2-second duration. Achieving IOP in range of 8–21 mmHg at one month was considered as scucessful. Results: The mean age of participants was 45.59 ± 11.52 years, with 43 (58.90%) aged 41–65 years. The majority were male (68.49%), with a male-to-female ratio of 2.17:1. DLCA success was achieved in 60 patients (82.19%). Conclusion: DLCA is an effective, rapid, and cost-efficient procedure for managing refractory glaucoma, providing a viable alternative in resource-limited settings.
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Bernardi, E., & Töteberg-Harms, M. (2022). First and second transscleral cyclophotocoagulation treatments provide similar intraocular pressure-lowering efficacy in patients with refractory glaucoma. International Ophthalmology, 42(8), 2363-2369. https://doi.org/10.1007/s10792-022-02234-4
Anand, N., Klug, E., Nirappel, A., & Solá-Del Valle, D. (2020). A review of Cyclodestructive procedures for the treatment of glaucoma. Seminars in Ophthalmology, 35(5-6), 261-275. https://doi.org/10.1080/08820538.2020.1810711
Hamza, U., Asghar, W., Chaudhry, Q., L, Mehmood, F., Kazmi, S, Butt, H., M, et al. (2020). Trans scleral diode laser cycloablation for treatment of refractory glaucoma. P J M H S. 14(1), 126-9. https://pjmhsonline.com/2020/jan_march/pdf/126.pdf
Yu, Q., Liang, Y., Ji, F., & Yuan, Z. (2020). Comparison of ultrasound cycloplasty and transscleral cyclophotocoagulation for refractory glaucoma in Chinese population. BMC Ophthalmology, 20(1). https://doi.org/10.1186/s12886-020-01655-y
Tawfik al-Rubaie, M., & Abass ALshamarti, S. (2019). The efficacy of trans-scleral diode laser cyclophoto coagulation for the treatment of glaucoma that is resistant to the convential treatment (refractory glaucoma). AL-QADISIYAH MEDICAL JOURNAL, 15(2), 13-15. https://doi.org/10.28922/qmj.2019.15.2.13-15
Raja, V., Nagdev, N., Saurabh, K., & Reddy, S. (2022). Role of trans-scleral diode cyclophotocoagulation in refractory glaucoma: A large retrospective study. TNOA Journal of Ophthalmic Science and Research, 60(2), 142. https://doi.org/10.4103/tjosr.tjosr_27_22
Gabr, A., El Razeq, M., & Abdalla, A. (2019). Comparative study of two different techniques of diode laser transscleral cyclophotocoagulation in management of refractory glaucoma. Journal of the Egyptian Ophthalmological Society, 112(4), 154. https://doi.org/10.4103/ejos.ejos_66_19
Gabr, A., Nassef, M., Othman, T. E., & Hussein, T. (2020). Management of refractory glaucoma using fixed-energy diode laser cyclophotocoagulation. Delta Journal of Ophthalmology, 21(2), 117. https://doi.org/10.4103/djo.djo_60_19
Shakir, M., Bokhari, S. A., Shakir Zafar, Z. K., & Rizvi, S. F. (2012). Transscleral Diode Laser Cyclophotocoaglation for Refractory Glaucoma. Pakistan Journal of Ophthalmology, 28(1). https://doi.org/10.36351/pjo.v28i1.450
Mahmood, K., Khan, M. T., Butt, J. B. Y., & Qureshi, T. (2011). Diode Laser Trans –Scleral Cyclo –ablation as a Primary Surgical Treatment for Primary Open –Angle Glaucoma after Maximum Tolerated Medical Therapy. Annals of King Edward Medical University, 17(2), 157-157. https://doi.org/10.21649/akemu.v17i2.291
Butt, J. B. Y., Qureshi, T. M., Khan, M. T., & Ahmad, A. U. H. (2014). Diode Laser Trans-Scleral Cycloablation as Surgical Treatment for Primary Open? Angle Glaucoma after Maximum Tolerated Medical Therapy. Pakistan Journal of Ophthalmology, 30(2). https://doi.org/10.36351/pjo.v30i2.290
Mahmood, K., & Baig, R. A. (2007). Transscleral diode laser cyclophotocoagulation for the treatment of refractory glaucoma. Pakistan Journal of Ophthalmology, 23(4). https://doi.org/10.36351/pjo.v23i4.754
Kuzhuppilly, N. I., Dev, S., Patil, S. N., & Deo, A. (2020). Outcome of Transscleral Cyclophotocoagulation in Refractory Glaucoma at a Tertiary Eye Hospital in India. Indian Journal of Public Health Research & Development, 11(6), 520-526.
Yelenskiy, A., Gillette, T. B., Arosemena, A., Stern, A. G., Garris, W. J., Young, C. T., Hoyt, M., Worley, N., Zurakowski, D., & Ayyala, R. S. (2018). Patient Outcomes Following Micropulse Transscleral Cyclophotocoagulation: Intermediate-term Results. Journal of Glaucoma, 27(10), 920–925. https://doi.org/10.1097/ijg.0000000000001023
Issiaka, M., Zrikem, K., Mchachi, A., Benhmidoune, L., Rachid, R., Belhadji, M. EL., Salam, A., & Abdou Amza. (2023). Micropulse diode laser therapy in refractory glaucoma. Advances in Ophthalmology Practice and Research, 3(1), 23–28. https://doi.org/10.1016/j.aopr.2022.10.003
Aquino, M. C. D., Barton, K., Tan, A. M. W., Sng, C., Li, X., Loon, S. C., & Chew, P. T. (2014). Micropulse versus continuous wave transscleral diode cyclophotocoagulation in refractory glaucoma: a randomized exploratory study. Clinical & Experimental Ophthalmology, 43(1), 40–46. https://doi.org/10.1111/ceo.12360
Williams, A. L., Moster, M. R., Rahmatnejad, K., Resende, A. F., Horan, T., Reynolds, M., Yung, E., Abramowitz, B., Kuchar, S., & Waisbourd, M. (2018). Clinical Efficacy and Safety Profile of Micropulse Transscleral Cyclophotocoagulation in Refractory Glaucoma. Journal of Glaucoma, 27(5), 445–449. https://doi.org/10.1097/ijg.0000000000000934
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